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GLP-1 receptor agonists are a class 2 medical drug used to cure sweet diabetes.
Similar to glucagon, peptide-1 receptor agonists have excellent qualities that, beyond blood sugar control, have positive effects on blood pressure, body weight, beta abundance, and cholesterol levels.
They affect glucose control with the help of a variety of agents, including delaying gastric contents, shaving glucose-dependent insulin secretion, and reducing glucagon intake after meals.
They work by simulating the effects of the injectable hormone GLP-1, which responds to food intake in the intestinal tract.
NOTE GLP-1 receptor agonists do not cause hypoglycemia (low blood sugar). However, they can cause vomiting, diarrhea, nausea, asthenia, headache, or dizziness.
GLP-1 receptor agonists are injected once a day, twice a day, or once a week into the stomach, upper arm, or thigh.
This is a comparison of Trulicity and Bydureon, two GLP-1 sensor agonists.
Trulicity
Trulicity (Dulaglutide) is a GLP-1 sensor agonist administered once a week.
In 2014, it was approved by the U.S. Food and Drug Administration as an exercise and diet supplement to improve glycemic control in diabetic patients.2
Prepared by Ali Lilly and Farm.
Bydureon
Bydureon is an injectable medication used to improve glycemic control in people with sweet diabetes 2.
Bydureon (Exenatide) is the same product as Byetta, but Bydureon is produced more slowly and requires an injection every 7 days.
Mechanism
Byfureon works by attaching to the glucagon-like peptide 1 (GLP-1) receptor on the surface of pancreatic cells and to sensors of insulin release.
Bydureon functions like inertine, increasing the amount of insulin released by the pancreas in response to food.
Side Effects
Possible translational side effects.
- Feeling hunted;.
- Quick, benign rhythms.
- Restless sensation or shortness of breath.
- Vomiting;.
- Nausea;.
- Decreased appetite;.
- Severe pain in the upper abdomen.
- Swelling in feet and ankles.
- Diarrhea;.
- Stomach complaints;.
- Faint voice;.
- Painful or difficult to urinate.
- Swallowing problems;.
- Little or no urination;.
- Dizziness;.
- Swelling or lumps in the neck;
- Irritability;.
- Weakness;.
- Headache.
Possible side effects of byfrotheon include
- Vomiting;.
- decreased appetite
- Severe swelling of the lips, face, or tongue; and
- Itching at the injection site;.
- drowsiness;.
- Constipation;.
- Dizziness;.
- Weight loss;.
- Decreased renal function;.
- headache; headache; headache; headache; headache
- hair loss;.
- Weak feelings;.
- Stomach complaints;.
- Skin rash;.
- Acid reflux;.
- Dehydration;.
- Excessive gas in stomach and intestines.
- Inflammation of the pancreas;.
- Unusual taste in the mouth.
- Excessive sweating;.
- Abdominal pain or bloated sensation in the abdomen.
Dosage.
There are two doses that can be transported inexpensively: 0.75 mg and 1.5 mg. The initial dose is 0.75 mg subcutaneously once a week.
The maximum recommended dose is 1.5 mg subcutaneously once a week. This product should be taken weekly on the same day.
The recommended dose of Byndureon is subcutaneous (weekly) once a week (weekly on the same day) behind the arm, belly, or leg.
There is no need to be involved in these injections.
Warnings and Precautions
Trulicity
To make sure that this GLP-1 senseraedist is not harmful to you, you should inform your doctor or pharmacist if you are suffering from
- Kidney disease;.
- History of pancreatitis;.
- Liver disease;.
- Diarrhea or vomiting.
- If still using insulin or oral diabetes medications.
- Slow digestion;.
- Gastroesophageal reflux disease (GERD);.
- Stomach or intestinal complaints.
Use of this GLP-1 sensorianist is not recommended for patients under 18 years of age. Not for curing diabetic ketosidosis or sweet diabetes 1.
Bydureon
Do not use this GLP-1 sensera agonist for
- Undergo dialysis.
- Have serious kidney problems.
- You are allergic to one of the ingredients in the drug.
- You have diabetic ketoacidosis.
- You have diabetes mellitus 1 or a type of diabetes.
In addition, this GLP-1 SenseraEdisto is not recommended for children under 18 years of age or young adults.
drug interactions.
Trulicity may have negative interactions with the following medications
- Furosemide;.
- levothyroxine;.
- Glimepiride (anti-diabetic sulfonyl lumber);.
- Levemir (insulin detemir);.
- Glipizide (Glipizide)
- Lantus (Insulin Glargin);.
- Insulin
- January (Sitagliptine).
Byfureon may have adverse interactions with related medications.
- Aspirin;.
- Lisinopril;.
- Byetta;.
- Losartan;.
- Glimepiride;.
- Levothyroxine (synthetic form of thyroxine);.
- Levemir (insulin detemir);.
- Insulin
- Lantus (insulin glargine).
Alcohol.
Use of alcohol in combination with these GLP-1 receptors may cause interactions.
Do not use alcohol while using these diabetes medications.
Is it safe during pregnancy or breastfeeding?
If the mother is using this GLP-1 receptor agonist, it is not known if the fetus will be injured. Additionally, it is not clear if these diabetes medications turn into breast milk.
Before using these GLP-1 receptors, contact your physician if you are pregnant or breastfeeding.
trulicity-costs opposite of byfureon
Trulicity (Dulaglutide) – is a diabetic drug used in mature people with sweet diabetes 2 to control blood sugar levels. It works by stimulating the body’s natural insulin production. It is not prescribed for patients with diabetes 1 or other conditions.
Byfureon (exenatide), used alone or in conjunction with other diabetes medications, increases blood sugar levels in diabetics 2. It mimics the effects of the natural hormone GLP-1. It is not insulin and does not replace insulin.
Experts say the GLP-1 sensory device is considered a valuable variation for the treatment of type 2 diabetes, either as a monotherapy or as an add-on therapy. This is because it effectively lowers A1C and at the same time lowers the risk of hypoglycemia.
In addition, clinical studies have shown the benefits of GLP-1 receptor agonists in relation to other antidiabetic drugs in the areas of blood pressure reduction and weight loss.
As for pricing, Transitic costs about $770; Byfureon costs about $697. U.S. for delivery of 4 powders for injection.
Alternatives to Bydureon and Trulicity
- exatide (Byetta); and
- liraglutide (Victoza, Saxenda); and
- semiglutide (ozempic);.
- lixiside (lixumia);.
- albiglutide (Tanzeum).
Source https: // www. nejm. org/doi/full/10. 1056/nejmoa1612917 https: // www. astrazeneca-us. com/media/press-releases/2017/bydueon-sexcel- trial https: // www. ncbi. nlm. nih (National Institutes of Health. gov/pmc/orties/pmc4665063/
