Primary immune response

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Certain cells and special proteins work together in the body to form the body immune system that protects you from infection. The immune Systems located throughout the body that provide rapid protection from infection. immune responses Where infection occurs. The immune Cells pass through the blood vessels and lymphatic system of the circulation. Our immune system has primary immune response And then there is the secondary response . In the association between the immune There are special structures in the lymph nodes and spleen to assure the cells

What is this initial immune response?

To protect you from bacteria, microbes, and other external medicines (called antigens) the the immune The system must recognize and develop these drugs a response .

Primary response

At the first contact with the antigen a primary response space. After an incubation period, which usually lasts several days, a type of antibody in the blood begins to become visible.

Secondary Response

In future and future times when you encounter this antigen, your body develops a repeated RH factor. immune response This will be larger and faster. It will be larger, develop faster, and have less antigen to trigger the response.

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Difference between primary and secondary immune response.

Primary immune response

Four stages of primary immune response

When someone is exposed to an antigen they have never seen before, a relatively short-lived and weak immune response , the primary immune response An immune response occurs. This phase can be subdivided into four phases: delayed phase, exponential phase, fixed phase, and regression phase.

This is the period from the initial impact of the antigen to the detection of antibodies in the blood and lasts up to one week. During this time, special B and T cells are activated by contact with the antigen.

Here there is a rapid increase in the value of antibodies, which are excreted by a large number of plasma cells (differentiated B cells).

The level of antibodies remains relatively unchanged by the constant isolation of antibodies to compensate for the denatured antibodies.

As existing plasma cells die, antibody levels slowly decline and no new plasma cells are formed to replace them. Since immunogenicity is probably eliminated from the body, no further antibody production is required.

Secondary immune response

Repeated (amntic) if two or more encounters with similar antigens immune responses Performance. Here, the latent phase is short and the highest and most stable antibodies are produced within a few days. This is due to the antigen-specific memory of T and B cells, initially created in the latent phase. the primary response .

Due to the secondary rate. immune response Antigens have a chance to be eliminated fast enough after they enter the body before the disease causes them. Acquired antibodies remain in circulation for a longer period of time to ensure that the infection has disappeared.

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Primary vs. secondary immune response

Primary immune response

Secondary immune response

After initial exposure to the strange antigen, there is a delayed phase in which B cells differentiate into plasma cells but have not yet produced antibodies. Antibody production can vary from 2 days to several months.

If a previously discovered RH factor reenters the body, a secondary RH factor may develop days to years later. immune response Development. During this phase, the delay is significantly reduced by about 3 to 4 days.

Usually, a small number of antibodies are present.

Numerous antibodies are filled.

After a short time, the antibody count decreases to a minimum.

Antibody levels remain elevated longer.

Antibodies are usually IgM, but IgG antibodies are also produced.

IgG is considered the most important antibody excreted.

Watch this video to get an idea of primary and secondary immune responses.

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Alex Koliada, PhD

Alex Koliada, PhD

Alex Koliada, PhD, is a well-known doctor. He is famous for his studies of ageing, genetics and other medical conditions. He works at the Institute of Food Biotechnology and Genomics NAS of Ukraine. His scientific researches are printed by the most reputable international magazines. Some of his works are: Differences in the gut Firmicutes to Bacteroidetes ratio across age groups in healthy Ukrainian population [BiomedCentral.com]; Mating status affects Drosophila lifespan, metabolism and antioxidant system [Science Direct]; Anise Hyssop Agastache foeniculum Increases Lifespan, Stress Resistance, and Metabolism by Affecting Free Radical Processes in Drosophila [Frontiersin].
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