Diphenhydramine treats allergic-type reactions by blocking histamine-1 (H1) receptors. This prevents histamine from having an effect on the airways, blood vessels, and on the gastrointestinal tract, reversing symptoms such as bronchoconstriction (narrowing of the airways), rash and itch, and stomach cramps. Pink Pill 44-329 also blocks acetylcholine receptors, sodium channels, and inhibits the reuptake of serotonin, among other effects. These latter effects are responsible for its sedative effects and side effects such as dry mouth.
Diphenhydramine Hcl – Uses, Side Effects, and More
Diphenhydramine is an antihistamine used to relieve symptoms of allergy, hay fever, and the common cold. These symptoms include rash, itching, watery eyes, itchy eyes/nose/throat, cough, runny nose, and sneezing. It is also used to prevent and treat nausea, vomiting and dizziness caused by motion sickness. Diphenhydramine can also be used to help you relax and fall asleep.This medication works by blocking a certain natural substance (histamine) that your body makes during an allergic reaction. Its drying effects on such symptoms as watery eyes and runny nose are caused by blocking another natural substance made by your body (acetylcholine).Cough-and-cold products have not been shown to be safe or effective in children younger than 6 years. Do not use this product to treat cold symptoms in children younger than 6 years unless specifically directed by the doctor. Some products (such as long-acting tablets/capsules) are not recommended for use in children younger than 12 years. Ask your doctor or pharmacist for more details about using your product safely.These products do not cure or shorten the length of the common cold and may cause serious side effects. To decrease the risk for serious side effects, carefully follow all dosage directions. Do not use this product to make a child sleepy. Do not give other cough-and-cold medication that might contain the same or similar ingredients (see also Drug Interactions section). Ask the doctor or pharmacist about other ways to relieve cough and cold symptoms (such as drinking enough fluids, using a humidifier or saline nose drops/spray).
How to use Diphenhydramine Hcl
Follow all directions on the product package. If your doctor has prescribed this medication, take it as directed. If you have any questions, ask your doctor or pharmacist.
Take the tablet, capsule, or liquid form by mouth with or without food. Measure liquid forms of this medication using a special measuring device/spoon. Do not use a household spoon because you may not get the correct dose. If you have a single-dose form of this medication (such as a single-use whistle), you do not need to measure the dose.
The rapidly-dissolving tablet or strip should be allowed to dissolve on the tongue and then swallowed, with or without water. The chewable tablets should be chewed thoroughly before being swallowed.
The dosage is based on your age, medical condition, and response to treatment. There are many brands and forms of diphenhydramine available. Read the dosing instructions carefully for each product because the amount of diphenhydramine may be different between products. Do not increase your dose or take this medication more often than directed.
To prevent motion sickness, take your dose 30 minutes before starting activity such as travel. To help you sleep, take your dose about 30 minutes before bedtime. If you continue to have difficulty sleeping for longer than 2 weeks, contact your doctor.
Tell your doctor if your condition does not improve or if it worsens.
Side Effects
Drowsiness, dizziness, constipation, stomach upset, blurred vision, or dry mouth/nose/throat may occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly.
To relieve dry mouth, suck (sugarless) hard candy or ice chips, chew (sugarless) gum, drink water, or use a saliva substitute.
If your doctor has directed you to use this medication, remember that your doctor has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.
Tell your doctor right away if you have any serious side effects, including: mental/mood changes (such as restlessness, confusion), difficulty urinating, fast/irregular heartbeat.
Get medical help right away if you have any very serious side effects, including: seizures.
A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.
This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.
In the US – Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.
In Canada – Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.
Precautions
Before taking diphenhydramine, tell your doctor or pharmacist if you are allergic to it; or to dimenhydrinate; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
Before using this medication, tell your doctor or pharmacist your medical history, especially of: breathing problems (such as asthma, emphysema), high pressure in the eye (glaucoma), heart problems, high blood pressure, liver disease, seizures, stomach/intestine problems (such as ulcers, blockage), overactive thyroid (hyperthyroidism), difficulty urinating (for example, due to enlarged prostate).
This drug may make you dizzy or drowsy or blur your vision. Alcohol or marijuana (cannabis) can make you more dizzy or drowsy. Do not drive, use machinery, or do anything that needs alertness or clear vision until you can do it safely. Avoid alcoholic beverages. Talk to your doctor if you are using marijuana (cannabis).
Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).
Liquid products, chewable tablets, or dissolving tablets/strips may contain sugar and/or aspartame. Liquid products may also contain alcohol. Caution is advised if you have diabetes, liver disease, phenylketonuria (PKU), or any other condition that requires you to limit/avoid these substances in your diet. Ask your doctor or pharmacist about using this product safely.
Children may be more sensitive to the side effects of this drug. This drug can often cause excitement in young children instead of drowsiness.
Older adults may be more sensitive to the side effects of this drug, especially drowsiness, dizziness, confusion, constipation, or trouble urinating. Drowsiness, dizziness, and confusion can increase the risk of falling.
During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.
This drug passes into breast milk and may have undesirable effects on a nursing infant. Consult your doctor before breast-feeding.
7 Facts About Pink Pill 44-329 You Should Know
The pink oval pill with the imprint 44 329 has been identified as Diphenhydramine Hydrochloride 25 mg supplied by Major Pharmaceuticals Inc. Diphenhydramine is used in the treatment of allergic reactions; allergic rhinitis; insomnia; cough; cold symptoms and belongs to the drug classes anticholinergic antiemetics, anticholinergic anti-parkinson agents, antihistamines, miscellaneous anxiolytics, sedatives and hypnotics. There is no proven risk in humans during pregnancy. Diphenhydramine 25 mg is not a controlled substance under the Controlled Substances Act (CSA).
How Pink Pill 44-329 works
Diphenhydramine is an antihistamine that may be used for the treatment of allergies, motion sickness, to help induce sleep, and to relieve symptoms of Parkinson’s Disease.
Diphenhydramine treats allergic-type reactions by blocking histamine-1 (H1) receptors. This prevents histamine from having an effect on the airways, blood vessels, and on the gastrointestinal tract, reversing symptoms such as bronchoconstriction (narrowing of the airways), rash and itch, and stomach cramps. Pink Pill 44-329 also blocks acetylcholine receptors, sodium channels, and inhibits the reuptake of serotonin, among other effects. These latter effects are responsible for its sedative effects and side effects such as dry mouth.
Diphenhydramine belongs to the class of medicines known as first generation antihistamines. Diphenhydramine is an antihistamine of the ethanolamine class.
The Upsides of Pink Pill 44-329
- Pink Pill 44-329 is used to treat the symptoms of allergic-type reactions such as sneezing, itching, watery eyes, and runny nose.
- May be used for the treatment of allergies, insect bites, hay fever, allergic conjunctivitis, urticaria (hives), and in addition to epinephrine for anaphylactic reactions.
- May be used to relieve the symptoms of nausea and vomiting associated with motion sickness.
- Can be used to help people relax or fall asleep.
- May also be used for elderly people with Parkinson’s disease who are unable to tolerate more potent agents.
The Downsides of Pink Pill 44-329
If you are between the ages of 18 and 60, take no other medication or have no other medical conditions, side effects you are more likely to experience include:
- Drowsiness and sedation which may impair judgment and affect a person’s ability to drive or operate machinery. Alcohol should be avoided because it can make this side effect worse.
- Dizziness, low blood pressure, a headache, rapid heart beat, disturbed coordination, abdominal discomfort and a thickening of mucus in the airways may also occur.
- May cause a dry mouth, which may increase the risk of dental caries and worsen the symptoms of gastroesophageal reflux disease (GERD) if diphenhydramine is used on a regular basis.
- Not suitable for use in women who are breastfeeding or young children. Elderly people may be more susceptible to the side effects of sedation, dizziness, and low blood pressure (all of which may increase their risk of falls).
- Overdosage of diphenhydramine has been associated with hallucinations, convulsions, and death.
- May interact with a number of other drugs including benzodiazepines, antidepressants, antipsychotics, and alcohol.
- May not be suitable for some people including those with respiratory diseases such as asthma, narrow-angle glaucoma, peptic ulcer disease, intestinal obstruction, high blood pressure or heart disease, high thyroid levels, an enlarged prostate, or a narrowing of the neck of the bladder.
Notes: In general, seniors or children, people with certain medical conditions (such as liver or kidney problems, heart disease, diabetes, seizures) or people who take other medications are more at risk of developing a wider range of side effects. For a complete list of all side effects.
Tips
- Pink Pill 44-329 may be taken with or without food.
- Take exactly as directed. Do not take more than is recommended.
- Do not drive or operate machinery if Pink Pill 44-329 makes you drowsy or affects your judgment. Avoid alcohol.
- When used for motion sickness, take Pink Pill 44-329 30 minutes before any exposure to motion. Take subsequent doses before meals or at bedtime for the duration of the exposure.
- Pink Pill 44-329 should not be used as a night time sleep aid in children aged less than twelve.
- Ensure you maintain good oral hygiene if you are taking Pink Pill 44-329 long-term.
- Stand up slowly when going from a sitting or lying down position. Pink Pill 44-329 may cause a drop in blood pressure which may cause symptoms such as dizziness and increase your risk of falls. Remove any fall hazards in your home (such as rugs) and talk to your doctor if you are experiencing severe dizziness every time you stand up.
- Seek urgent medical advice if you experience any symptoms such as agitation, hallucinations, a fast heart rate, dizziness, flushing, muscle tremor or rigidity, nausea, vomiting or diarrhea.
- Talk to your doctor or pharmacist before taking any other medications while you are taking Pink Pill 44-329.
Response and Effectiveness of Pink Pill 44-329
Diphenhydramine is quickly absorbed after oral administration and peak effects are reached within one hour. The effects of diphenhydramine last from four to six hours.
When used as a night-time sleeping aid, the usual dosage of diphenhydramine is 50mg at bedtime. A lower dosage may be needed in the elderly.
Interactions
Medicines that interact with Pink Pill 44-329 may either decrease its effect, affect how long it works for, increase side effects, or have less of an effect when taken with diphenhydramine. An interaction between two medications does not always mean that you must stop taking one of the medications; however, sometimes it does. Speak to your doctor about how drug interactions should be managed.
Common medications that may interact with diphenhydramine include:
- benzodiazepines, such as diazepam, oxazepam, and temazepam
- monoamine oxidase inhibitors, such as isocarboxazid, selegiline, or tranylcypromine
- opioids, such as oxycodone, morphine, or codeine
- sedatives, or any medication that causes sedation, such as sleeping pills, muscle relaxants, or antidepressants
- other medications that contain diphenhydramine, such as creams and gels
- other medications used to treat allergies.
Alcohol may enhance the sedative effects of diphenhydramine.
Note that this list is not all-inclusive and includes only common medications that may interact with diphenhydramine. You should refer to the prescribing information for diphenhydramine for a complete list of interactions.
Summary
Pink Pill 44-329 is an antihistamine that can be used to treat allergic reactions, relieve motion sickness, as a sleep aid, and to relieve some symptoms of Parkinson’s disease. Sedation is a common side effect.
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