If these symptoms are mild, they probably won’t bother you. However, if you feel that these side effects are severe or if they don’t go away, contact your doctor.
Side Effects of Mucinex DM (guaifenesin and dextromethorphan hydrobromide)
Mucinex DM (guaifenesin and dextromethorphan hydrobromide tablet, extended release) is a combination of an expectorant and cough suppressant used to help loosen phlegm (mucus) and thin bronchial secretions to rid the bronchial passageways of bothersome mucus and make coughs more productive.
Mucinex DM temporarily relieves cough due to minor throat and bronchial irritation as may occur with the common cold or inhaled irritants, the intensity of coughing, and the impulse to cough to help you get to sleep. Mucinex DM is available over-the-counter (OTC).
Common side effects of Mucinex DM include dizziness, drowsiness, nausea, and vomiting.
If pregnant or breastfeeding, ask a health professional before use.
What are the side effects of Mucinex DM?
What are the serious side effects of Mucinex DM?
Mucinex DM may cause serious side effects including:
- hives,
- difficulty breathing,
- swelling of your face, lips, tongue, or throat,
- severe dizziness,
- rash, and
- itching
Get medical help right away, if you have any of the symptoms listed above.
What are the common side effects of Mucinex DM?
The most common side effects of Mucinex DM include:
Tell the doctor if you have any side effect that bothers you or that does not go away.
These are not all the possible side effects of Mucinex. For more information, ask your doctor or pharmacist.
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Is Mucinex DM addictive?
No information provided
What drugs interact with Mucinex DM?
No information provided
Side effect list for healthcare professionals
No information provided
Summary
Mucinex DM (guaifenesin and dextromethorphan hydrobromide tablet, extended release) is a combination of an expectorant and cough suppressant used to help loosen phlegm (mucus) and relieve cough symptoms. Common side effects of Mucinex DM include dizziness, drowsiness, nausea, and vomiting.
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Cough: 19 Tips on How to Stop a Cough
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Common Cold
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Cold Sores (Oral Herpes, Herpes Labialis)
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Chronic Cough
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Flu (Influenza)
Influenza (flu) is a respiratory illness caused by a virus. Flu symptoms include fever, cough, sore throat, runny nose, headache, fatigue, and muscle aches. The flu may be prevented with an annual influenza vaccination.
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If you have diabetes and catch a cold or the flu, can be more difficult to recover from infections and their complications, for example, pneumonia. Home remedies and over-the-counter (OTC) drugs used for the treatment of the signs and symptoms of colds and the flu may affect blood sugar levels in people with diabetes.Some medications are OK to take if you have diabetes get a cold or the flu include nonsteroidal anti-inflammatory drugs or NSAIDs, like acetaminophen (Tylenol) and ibuprofen (Motrin) to control symptoms of fever and pain. Most cough syrups are safe to take; however, check with your pediatrician to see what medications are safe to give your child if he or she has type 1 or 2 diabetes. If you have diabetes and are sick with a cold or flu, you need to check your blood sugar levels more frequently. Continue taking your regular medications. Eat a diabetic low-glycemic index diet rich in antioxidants. To prevent colds and the flu drink at least eight 8 ounce glasses of water a day. To replenish fluids, drink sports drinks like Gatorade and Pedialyte to replenish electrolytes. Avoid people who are sick, sneezing, coughing, or have other symptoms of a cold or flu.
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Human body is capable of maintaining a steady core temperature between 97°F and 99°F. However, it is essential to layer up in cold weather and wear comfortable clothes in warm weather, so that we stay protected from extremes of temperature.
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Viruses cause the common cold and the flu. Early symptoms and signs for a cold and the flu are similar, however, flu symptoms are typically more severe than cold symptoms. Cold and flu viruses are transmitted typically via coughing or sneezing.
How Do You Get Rid of a Cold Overnight?
Cold symptoms are part of your body’s healing processes. Most of the time, it does not require any help. However, you can get rid of a cold faster, even overnight, by resting, drinking hot fluids, blowing your nose, gargling with salt water, taking a hot shower, using a humidifier and taking OTC pain relievers and decongestants.
What Can I Take for a Cough While Pregnant?
Seasonal flu, colds, and allergies are common ailments affecting most people all round the year. You must always be cautious of any medication that you take. This is especially true in pregnancy and during breastfeeding, given the effects these drugs may have on the unborn or breastfed child.
What Happens if a Pregnant Woman Gets a Cold?
Having an ordinary cold shouldn’t be harmful to the baby or mother. Pregnant women are highly likely to pick up a cold at some time during pregnancy because it’s normal to catch two or three colds a year. A healthy lifestyle is a must to keep the immune system strong and to prevent colds.
Are Cold Sores (Fever Blisters) Contagious?
About 20% of cases of cold sores are caused by herpes simplex virus type 2 (HSV-2), and approximately 80% of cold sores are caused by herpes simplex virus type 1 (HSV-1). Cold sores are transmitted by sharing utensils and razors, kissing, and oral sex. There is no cure for cold sores.
Are Cold Sores the Same as Herpes?
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COVID-19 vs. Flu vs. Cold
When you’re feeling sick, it can be difficult to distinguish the symptoms of a COVID-19 infection from the symptoms of the common cold or the flu (influenza). While fever is common with the flu and COVID-19, sneezing is typically only associated with colds. Though sore throats are typical with colds, they are uncommon with COVID-19 infections and the flu.
Cold vs. Flu
Though the common cold and flu share many signs and symptoms, they are caused by different viruses. Signs and symptoms include sneezing, sore throat, runny nose, fatigue, and cough. Treatment options for the cold and flu are similar and focus on reducing symptoms. Doctors may prescribe antivirals/neuraminidase inhibitors for the flu.
Whooping Cough (Pertussis)
Whooping cough (pertussis) is a highly contagious respiratory infection caused by the bacteria Bordetella pertussis. There are an estimated 300,000 plus deaths annually from whooping cough (pertussis). Whooping cough commonly affects infants and young children but can be prevented with immunization with the vaccine. First stage whooping cough symptoms are a runny nose, sneezing, low-grade fever, a mild cough with the cough gradually becoming more severe. After one to two weeks, the second stage of whooping cough begins.
How Can I Stop My Child From Coughing?
Treatment for cough is not recommended unless the cough interferes with the child’s sleep or activity or is accompanied by a fever. Different age groups of children require different therapies to stop them from coughing. Some good home remedies to treat cough in children include honey, warm milk, hydration, steam inhalation, resting, saline nose drops and other strategies.
Cold, Flu, Allergy Treatments
Before treating a cold, the flu, or allergies with over-the-counter (OTC) medications, it’s important to know what’s causing the symptoms, which symptoms one wishes to relieve, and the active ingredients in the OTC product. Taking products that only contain the medications needed for relieving your symptoms prevents ingestion of unnecessary medications and reduces the chances of side effects.
How Do I Get Rid of a Cold Sore Overnight?
You cannot get rid of cold sores overnight. There is no cure for cold sores. However, to speed up the healing time of a cold sore, you can consult with your doctor and take prescription medications such as antiviral tablets and creams. A cold sore may go away without treatment within a week or two.
Genital Herpes and Cold Sores: 10 Myths and Facts
Genital herpes and cold sores (oral herpes) are the names given to two types of infection caused by the two types of herpes simplex virus (HSV): HSV-1 and HSV-2.
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Children’s cough causes include infection, acid reflux, asthma, allergies or sinus infection, whooping cough, and exposure to irritants. Treatment for a child’s cough include cough medicine for children over the age of four.
Is Drinking Cold Water Bad?
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Sinus Infection vs. Cold
Viruses cause the common cold and most sinus infections. Bacterial and fungal infections may also cause a sinus infection. Signs and symptoms of colds and sinus infections include nasal irritation or dryness, sore throat, stuffy nose, nasal discharge/congestion, sneezing, and cough. Additional symptoms of sinus infections include sinus pressure behind the cheeks or eyes, facial pain when pressure is applied, bad breath, and thick yellow or green mucus. Treatment focuses on symptom relief.
How Do You Cure the Flu Quickly?
Flu or influenza is a common viral disease affecting the respiratory system. This infectious disease is caused by the influenza virus. Most cases of flu are self-limiting and can be easily managed at home.
How Long Does Whooping Cough Last?
What is whooping cough and how long does whooping cough last? Learn more about whooping cough and how to recover from whooping cough.
Is It a Cold or a Sinus Infection?
A sinus infection, also known as sinusitis or rhinosinusitis, is a condition in which the delicate membranes that line the sinuses may get swollen and become red. A cold or common cold is a viral infection. It affects the upper respiratory system, which includes the nose, mouth, throat, and lungs.
What Is the Best Treatment for Whooping Cough?
Learn what medical treatments can help ease your whooping cough symptoms and speed up your recovery.
What Can You Take for a Cold While Pregnant?
You may take over-the-counter (OTC) treatment after consulting with the physician because these are generally safe. OTC medications for colds and flus include acetaminophen, guaifenesin syrup and saline nasal drops or spray. You can also use natural remedies to treat a cold during pregnancy.
How Serious Is Whooping Cough in Adults?
What is whooping cough (pertussis) and how serious is it for adults? Learn causes, symptoms and treatments.
Is Whooping Cough (Pertussis) Contagious?
Whooping cough (pertussis) is a highly contagious respiratory infection caused by Bordetella pertussis. Whooping cough symptoms include severe coughing fits and whooping sound produced during inhalation. The bacteria spreads via airborne droplets produced during sneezing or coughing. There is a whooping cough vaccine that is typically administered during childhood vaccinations.
Emphysema, Chronic Bronchitis, and Colds
If you have a COPD such as emphysema, avoiding chronic bronchitis and colds is important to avoid a more severe respiratory infection such as pneumonia. Avoiding cigarette smoking, practice good hygeine, stay away from crowds, and alerting your healthcare provider if you have a sinus infection or cold or cough that becomes worse. Treatment options depend upon the severity of the emphysema, bronchitis, or cold combination.
How Can Teens Cope With A Cold?
Usually, teens have a healthy immune system to cope with common cold. Getting plenty of rest and drinking lots of fluids can ease the symptoms.
What Can Trigger a Cold Sore?
After you get infected with HSV, it lies inactively in the nerve cells inside your skin and may appear as another cold sore at the same place as before.
How Do You Know If Your Child Has Whooping Cough?
Whooping cough is a common issue that affects many children. Learn the signs of whooping cough, what causes it, how doctors diagnose it, and what you can do to treat it.
How Long Are You Contagious With the Flu?
The flu is contagious 1-2 days before symptoms start and up to 5-7 days after symptoms have developed. Young children and people who have weak immune systems may be contagious for longer.
What Can I Do for My Baby’s Cough?
Cough can cause significant discomfort to a baby. The baby may also have difficulty relaxing and sleeping. Numerous illnesses can cause cough as a primary symptom. Coughing is the result of the baby’s airway being affected or irritated.
How Do I Get Rid of My Toddler’s Cough?
Cough is one of the common complaints in toddlers. Get rid of your toddler’s cough by making sure your child rests, stays hydrated, takes over-the-counter pain medication, uses nasal spray and uses a humidifier or steam to provide relief.
What Do You Give a Child With a Cold?
Unfortunately, there is no cure for the common cold. Antibiotics may be used to fight bacterial infections, but they have no effect on viruses.
What Is Good for a Child’s Cold?
The common cold is one of the main reasons for missing schools in children and missing work in adults. Children are affected more commonly with cold than adults, who may have an average of two to three colds each year.
How Do You Tell If Your Child Has Allergies or a Cold?
Colds and allergies have different causes, but both involve the body’s immune system. Since the symptoms of allergies and the symptoms of a cold overlap, it can be hard to tell which one your child has.
How Do You Treat a Cold Naturally?
Hundreds of viruses and bacteria can cause the common cold and flu. Most cases of cold and flu usually resolve in a week with simple home remedies and over the counter (OTC) medications. If there is no improvement in a few days, it is advised to consult a doctor.
How to Identify Cold Symptoms in Children
When a child is sick, their way of showing it may not always be clear. Here’s what to look for to determine whether your child is sick with a cold.
Side Effects of Mucinex D
Cold and allergy symptoms can really be bothersome. Sometimes, you just need a little relief. There are several over-the-counter drugs that can help, including Mucinex D.
Mucinex D contains two active ingredients: guaifenesin and pseudoephedrine. Guaifenesin helps loosen mucus in your chest. Pseudoephedrine temporarily helps with congestion in your nose. Together, these two ingredients work well to relieve symptoms of the common cold and allergies. These include cough, stuffy nose, sneezing, and sinus congestion and pressure.
However, there are side effects associated with the ingredients in this medication that you should know about.
Mucinex D works by combining the actions of the drugs guaifenesin and pseudoephedrine. Each ingredient can affect different parts of your body in different ways. Here are the effects you should be aware of while you take this drug.
Cardiovascular system effects
The pseudoephedrine in Mucinex D can affect your heart and increase your blood pressure. Symptoms of heart-related side effects include:
- increased heart rate
- pounding heart beat
If these symptoms are mild, they probably won’t bother you. However, if you feel that these side effects are severe or if they don’t go away, contact your doctor.
Nervous system effects
The active ingredients in Mucinex D can both affect your nervous system. However, these side effects are rare.
Most of the side effects of guaifenesin are mild and well-tolerated. They include:
- dizziness
- headache
- drowsiness
Nervous system side effects from pseudoephedrine can include:
- anxiety
- restlessness
- tremors
- headache
- lightheadedness
- dizziness
- sleeping trouble
Digestive system effects
Guaifenesin rarely causes stomach problems when you use it at recommended doses. Pseudoephedrine can cause the following side effects:
- nausea
- vomiting
- loss of appetite
If you experience nausea, try taking Mucinex D with food or a glass of milk.
Skin effects and allergic reaction
A possible side effect of Mucinex D is an allergic reaction. This may cause a skin rash. If you experience a rash after taking Mucinex D, stop taking it and contact your doctor.
If you notice any of the following, call 911 or local emergency services immediately:
- the rash is worsening
- you have swelling of your tongue or lips
- you have any difficulties breathing
Taking this drug if you have certain conditions increases your risk of severe side effects. Talk to your doctor before taking Mucinex-D if you have medical conditions such as:
- high blood pressure
- heart disease
- diabetes
- increased eye pressure
- thyroid problems
- prostate problems
It’s very important to use Mucinex D exactly as directed. Most of the severe side effects of Mucinex D can happen when you use too much. If you have any questions about how much you should use, ask your pharmacist.
The following side effects can occur if you use too much Mucinex D:
- changes in heart rhythm
- chest pain
- hallucinations
- heart attack
- seizures
- severe diarrhea
- severe increase in blood pressure
- severe nausea
- severe stomach pain
- severe vomiting
- stroke
- kidney stones
- brain or nerve damage
Symptoms of kidney stones include:
- fever
- chills
- vomiting
- severe, persisting pain in your back or side
- foul-smelling urine
- cloudy urine
- blood in your urine
- pain or burning when you urinate
- difficulty urinating
Symptoms of brain or nerve damage include:
- memory or vision loss
- arm and leg weakness
- coordination problems
Stop using Mucinex D and contact your doctor immediately if you have any of these severe side effects.
Maximum Strength Mucinex D contains double the amount of medicine. There are no additional side effects of the stronger formula as long as you take it as directed. However, taking the stronger formula at the dosage that’s recommended for the regular formula can lead to overuse and severe side effects.
Mucinex D can help most people relieve chest and nasal congestion without side effects that are harmful or worrisome. However, this is not true for everyone, especially if you have certain medical conditions or take other drugs.
If you’re unsure if Mucinex is right for you, ask your doctor. And if you can’t take Mucinex D, check out the best natural cough remedies and the best natural antihistamines.
Q:
When should I start feeling better?
A:
When taking Mucinex D, your symptoms should improve within 7 days. Stop taking it and call your doctor if your symptoms don’t go away or if they come back. Also, stop taking the drug if you develop a fever or rash. These could be signs of a more serious problem.
Answers represent the opinions of our medical experts. All content is strictly informational and should not be considered medical advice.
Last medically reviewed on July 25, 2016
How we reviewed this article:
Healthline has strict sourcing guidelines and relies on peer-reviewed studies, academic research institutions, and medical associations. We avoid using tertiary references. You can learn more about how we ensure our content is accurate and current by reading our editorial policy.
- Drug monograph: Guaifenesin; Pseudoephedrine. (2015, September)
clinicalkey.com/#!/content/drug_monograph/6-s2.0-1066 - Mucinex-D – guaifenesin and pseudoephedrine hydrochloride tablet, extended release. (2016, May)
dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=734bfd5f-146e-47ab-8326-cc66a25fc540 - Tietze, K. J. (2015). Cough. In D. L. Krinsky, S. P. Fereri, B. A. Hemstreet, A. L. Hume, G. D. Newton, C. J. Rollins, & K. J. Tietze (Eds.), Handbook of nonprescription drugs: An interactive approach to self-care (18 th ed.), 197-208. Washington, DC: American Pharmacists Association.
- U.S. National Library of Medicine. (2011, May). Guaifenesin
nlm.nih.gov/medlineplus/druginfo/meds/a682494.html - U.S. National Library of Medicine. (2014, February). Pseudoephedrine
nlm.nih.gov/medlineplus/druginfo/meds/a682619.html - U.S. National Library of Medicine. (2016, May). Kidney stones
nlm.nih.gov/medlineplus/kidneystones.html
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In 2024 our team of doctors and nurses provide a comprehensive range of family planning services. Our doctors have expertise in antenatal care, preconception planning, and STD checks. Contraceptive advice including Mirena and Implanon insertion is available.
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Our practice is dedicated to treating a wide spectrum of women’s health concerns. We offer pre-natal, antenatal and postnatal care, contraceptive options, pap screening, and preventative health care advice. We provide assistance, advice and support through all stages of life, recognising the many issues many women may face from adolescence through to the peri and post-menopausal period.
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