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Anemia is considered a common disorder characterized by layers of hemoglobin levels. There are many different types of anemia and they vary from lead base to lead base, but the end result of the accident unite to get unavailability of hemoglobin. Hemoglobin is the molecule that binds air from the blood and brings it to the tissues.
One of the most popular types of anemia is macrocytic anemia characterized by the presence of red blood cells. Causes of macrocytic anemia For his many, this subject deserves some discussion for a better understanding.
macrocytic anemia causes
Macrocytic anemias can be further subdivided into two main groups. First, there is megaloblastic anemia. macrocytic anemia This is considered the most common form. Until then, you have megaloblastic cells. macrocytic anemia This is usually the result of various serious medical problems such as liver or bone meror. In some cases, the cause of nonmegaloblasts cannot be virtually identified. of anemia .
Causes of megaloblastic anemia of megaloblasts
Bone marrow produces impure red blood cells (blush) before they end up in the bloodstream. If the immature erythrocytes have genetic tissue or DNA fractures, the cells become elevated before leaving the bone marrow and continue to rise when they end up in the bloodstream. These elevated immature red blood cells (called megaloblasts) are created by defective DNA production. The moment that causes defective DNA production in red blood cells also affects other cell types in the bone marrow (e.g., white blood cells). Eventually, both reddish and snow cells of megaloblasts can be seen under the microscope anemia appear abnormal.
One of thecommon macrocytic anemia The cause is medications, especially those that prevent folic acid from being metabolized and absorbed. These include methotrexate. This is a means used in the treatment of cancer, rheumatoid arthritis, antiepileptic drugs, anticancer drugs, HIV drugs, antidiabetic drugs (metformin) and antibacterial agents.
Vitamin B12 deficiency occurs only years later due to high concentrations of the drug in the liver. The condition can be: AutoimmuneadDison, adverse anemia Surgical deterioration such as ileal resection or gastrectomy, HIV infection, excessive bacterial hospitalization, parasitic damage, malnutrition, and dire consequences, in addition to the following anemia The condition often occurs in the elderly.
Folate deficiency can be caused by folate deficiency due to diet, malabsorption, hemolysis, leukemia, some skin diseases, pregnancy, acute hepatitis, cardiac deficiency, excessive excretion of folic acid by urine due to dialysis, skin diseases, pregnancy, excessive excretion in pregnancy.
Substances that cause folic acid deficiency include antikeratoblasts, alcohol, methotrexate, trimethoprim, and sulfasalazine.
Causes of Non-Megaloblastic Anemia
Causes of Non-Megaloblastoproliferative Anemia macrocytic anemia Not associated with defective DNA synthesis. Non-megaloblasts macrocytic anemia Less common and characterized by the absence of megaloblasts and the presence of adult but large erythrocytes. This pattern of erythrocytes usually occurs only in newborns. Conditions include
- chronic alcoholism
- liver disease
- hypothyroidism
- reticulocytosis
- Hematologic disorders such as aplasia and enrichment of red blood cells. anemia Myelodysplastic syndrome and myelopathy.
- Substances such as azathioprine.
- Pregnancy
Treatment of macrocytic anemia
Treatments depend on the macrocytic anemia causes and type of anemia Concern. Further evaluation and diagnosis is needed, which can be done with a test called a peripheral blood smear.
Diagnosis of macrocytic anemia
Blood smears are examined under a microscope to determine the size, shape, and number of red blood cells. Giant blast cells macrocytic anemia It is characterized by the presence of Howell-Jolly cells. These appear as small spots on the inside of the red blood cell. This indicates that these are red blood cells that have been released from the bone marrow in the bloodstream and startled to compensate. for anemia The patient still needs to be investigated for vitamin deficiency. The patient may still need to be investigated for vitamin deficiency.
Non-megaloblastic patients. macrocytic anemia Liver and bone marrow function should be investigated.
Treatment of megaloblastocytic anemia
Treatment of megaloblastocytic anemia anemia depends on the specific background and other factors such as age, general health, burden of disease, and response to treatment. This healing usually lasts for a long time.
when it is caused by vitamin B-12 deficiency:
Megaloblastic anemia Associated with vitamin B-12 deficiency is treated with monthly vitamin injections. You still have every opportunity to take oral supplements and eat products enriched with vitamin B-12 because it is recommended.
- Concentrated grains
- Milk
- Eggs
- Gauges
- Red meat
- Shellfish
When deficiency of folic acid is the cause:
Megaloblastic anemia Folic acid deficiency can be treated with intravenous or oral folic acid supplements. It is recommended to take a nutritional composition to increase folic acid levels. Foods high in folic acid include
- Leafy vegetables
- Oranges
- Enriched grains
- Peanuts
- Lentils
Non-Megaloblastic Tumor Cell Anemia Treatment
Treatment of Non-Megaloblastic Tumor Cell Anemia macrocytic anemia It is more complex because it is usually caused by an acquired disorder such as liver or bone marrow disease. Therefore, treatment is primarily aimed at healing the underlying condition, which is usually considered non-serious. Depending on the nature of the disease, a correct diagnosis must be made in order to heal and cure. & lt; pran & gt; related to folic acid deficiency can be treated with intravenous or oral folic acid supplements. It is recommended that a nutritional composition be taken to increase folic acid levels. Foods high in folic acid include
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