Gonal F Side Effects

Many readers are interested in the pertinent subjects: sting, dosage, cost, and side effects of Gonal-F for IVF use. Our makers are pleased to report that they have already done modern research studies on the subject that will fascinate you. We base our extensive answers on the latest medical reports, advanced research papers, and sample surveys. Keep repeating to find out more.

Additionally, Gonal-F is contraindicated in protective evaluations, where there are good ones.

gonal-f side effect center

Gonal-f (folitropine alfa) injection is considered a natural hormone used to stimulate the follicle (egg). Gonal-f is used when a woman is eager to conceive and the ovaries have had a chance to produce follicles, but hormonal stimulation is not sufficient to mature the follicles. Follicle – stimulating hormone (FSH) is still used to stimulate the formation of multiple egg cells for in vitro fertilization; FSH can be used by men to increase sperm production.

What are the side effects of Gonal-F?

Common side effects of Gonal-F include:

• Headache,
• Nausea,
• Vomiting and diarrhea,
• Slight abdominal/stomach pain,
• Pelvic pain or sensitivity,
• Abdominal bloating,
• Reaction to injection space (redness, pain, bruising, irritation),
• Swelling/ tenderness/ chest pain,
• Numbness or tingling,
• Runny or stuffy nose,
• Sore throat,
• Acne or
• skin rash.

Tell your own doctor if you have any of these almost impossible but responsible side effects. effects gonal-f, cover:

• Abnormal vaginal/uterine bleeding,
• Calf muscle pain/redness/swelling,
• Cold/foggy/pale skin on hands/feet/arms/legs, or
• swelling of ankles/arms/feet/legs.

gonal-f dosage

Doses of gonal-f for stimulation of follicle formation are individualized. The appropriate starting dose for the first cycle is 75 IU. Depending on the patient’s response, the dose may vary up to 300 IU per day.

Which drugs, medications, or supplements interact with gonal-f?

It is not known if other medications have interactions with gonal-f. Tell your doctor about any medications on prescription or any freely available medications or supplements you are using.

gonal-f during pregnancy and breastfeeding

It should not be used during pregnancy. Stop using gonal-f if you are pregnant. It is not clear if this product will convert to breast milk. Consult a physician before breastfeeding as it may cause damage to the baby.

Additional Information

Gonar F (follitropin alfa) Injection Drug Side Effects Center provides a comprehensive view of available drug information on side effects likely to occur with Gonar F (follitropin alfa) Injection. effects when using this medication.

This is not a complete list of parties effects and others may be available. For medical advice regarding a party, call your physician effects You can report a party effects FDA at 1-800-FDA-1088.

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Gonal-F Purchaser Information

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Seek emergency medical care if you have symptoms of an allergic reaction. Rough breathing; swelling of face, lips, tongue, or throat.

Some women using this medication may develop ovarian hyperstimulation syndrome (OHSS), a potentially life-threatening condition. If you develop signs of OHSS during or immediately after using follicle stimulating hormone, stop using this medication and contact your doctor immediately.

• Severe lower abdominal pain, feeling sick, diarrhea.
• Abdominal fullness, rapid weight gain.
• Little or no urination. Or
• Difficulty breathing.

Also, contact your physician immediately if you have any of the following symptoms

• Severe pelvic pain on one side.
• Coughing up bloody mucus.
• Fever, sore throat, swollen glands.
• Lump or swelling of the testicles.
• Signs of acute respiratory distress syndrome – shortness of breath or rapid breathing. or
• Signs of blood clots – numbness or impotence, difficulty seeing or speaking, swelling or redness of arms or legs.

Common side effects may include:

• Redness, swelling, or bruising at injection site.
• Ovarian cysts.
• Headache, fatigue;.
• Chest pain or swelling.
• Nasal congestion; sneezing; sinus pain.
• Acne; or
• Nausea.

This is not a complete list of parties effects and others may be available. For medical advice regarding a party, call your physician effects You can report a party effects FDA at 1-800-FDA-1088.

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GONAL-F Certification Information

Side Effects

The following serious side effects are discussed in other labeling sections

• Hypersensitivity Reactions and Anaphylaxis [see Warnings and Precautions].
• Ovarian Hyperstimulation Syndrome [see Warnings and Precautions].
• Pulmonary and Vascular Aggravation [see Warnings and Precautions].
• Ovarian torsion [see Warnings and Precautions].
• Abnormal ovarian enlargement [see Warnings and Precautions].
• Polyphthalmia Pregnancy and Delivery [see Warnings and Precautions].
• Embryofetal Toxicity [see Warnings and Precautions].
• External Pregnancy [see Warnings and Precautions].
• Spontaneous abortion [see Warnings and Precautions].
• EierSteplasmas [see Warnings and Precautions].

Clinical skills

Because clinical studies are conducted under very different circumstances, the characteristics of an adverse effect observed in a clinical study of a product are not likely to be exactly comparable to the characteristics observed in a clinical study of another product. It is more likely that these characteristics correspond to those actually observed.

Women

The safety of Gonal-F was investigated in four clinical studies involving 691 women [two ovulation induction studies (454 women) and two ART tests (237 women)].

Ovulation Induction

In a randomized, open, multichamber, centered, intensive check study in oligo-Anovulent infertile women in the United States, 118 oligo-Anovulent infertile women were randomized, ovulation induction was supplied, ovulation induction occurred, ovulation induction was given at 5, 0 and received gonal-f The percentages of women are shown in Table 1.

Table 1: Concurrent adverse reactions reported in U.S. ovulation induction studies with an incidence of 5% or greater.

Development of multiple follicles within a cycle of replacement reproductive technology (ART)

In an intensive care randomized discovery study conducted in the United States, 56 normal ovulating women were randomized with joint difficulties and gonal-f-f-framus comparators received ART [in vitro fertilization (IVF) or sperm injection intracytoplasmic cycle within a cycle. (ICSI)] cycle. All women were given pituitary down regulation with a gonadotropin-releasing hormone (GNRH) agonist prior to stimulation. Side effects that occurred in at least 5, 0% of women are shown in Table 2.

Table 2: Concurrent adverse reactions reported in U.S. ART studies with an incidence of at least 5%.

Induction of spermatogenesis

The safety of gonal-F for induction of spermatogenesis in men with primary or secondary gonadal gadaloplasmosis was examined in three open-label, nonrandomized, multichamber, multinational, escalated clinical studies (Studies 1, 2, and 3) conducted in 76 adult men (ages 16 to 48 ) with primary or secondary gonadal gadropic advanced hypogonadism (defined on the basis of serum testosterone).

During these studies, a 50-year-old man treated for 9 months with gonal-f had one responsible gynecomastia reaction requiring surgical removal of breast tissue. The pathology report documented gynecology without atypia.

There was virtually no stop settlement due to side effects.

The side effects reported in Tests 1, 2, and 3 support care for two or more patients during healing with gonal-f.

Table 3: Concurrent side effects in men with azospermia and initially vegetative hypogonadism received by gonal-f in Tests 1, 2, and 3 for induction of spermatogenesis

Marketing experience via email

In addition to the unwanted incidents reported from clinical testing, appropriate adverse reactions were reported during the use of the subsequently marketed gonal-f. Because these reactions themselves have been reported from populations of indefinite size, frequency or otherwise, a causal relationship to gonal-f cannot be determined.

General physical: hypersensitivity reactions, including anaphylaxis

Respiratory system: exacerbation of asthma

Vascular disorders: thromboembolism

Read all FDA prescribing information for gonal-f (follitropine alfa)

©Gonal-F patient information provided by Cerner Multum, Inc. Gonal-F buyer information provided by First DataBank, Inc. Used under license and subject to their respective copyrights.

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gonal-f injections for IVF use, dosage, cost, side effects

Gonal-F Shot is a fertility product with gonadotrophins used in ovarian stimulation cycles for IVF and other fertility enhancing cycles. Doses range from 75 to 1, 050 IU, but Gonal-F 300, Gonal-F 450, and Gonal-F 900 are most used.

Some doses of gonal-f are supplied in pens for subcutaneous injection. Depending on the dose, it can be used in IVF or IUI cycles.

Below is an 11 point index, which we hope to resolve in this message.

Description and Price

Gonal-F has an image of a hormone called recombinant FSH (R-FSH). It is produced to promote ovarian growth and development. Recombinant FSH is not of human origin (as in the case of menopur), but is formed with the help of genetic techniques in the laboratory.

Gonal-F has an active component follitropin alfa. Depending on the concentration of this hormone, gonal-f is sold in different types, each containing a specific composition.

Gonal-F can be found in two sizes. It distinguishes itself by the way it is entered.

Each gonal-f image has a different number of follitropin alphas. The physician administers a number corresponding to the number of FSH, which is important for the fertility healing cycle. Below are inexpensive doses and their costs

Gonal-F 75 75 IE/0, 5 mL (5, 5 micrograms). U.S. $100 per unit, approximate. gonal-F 300 IE/0, 5 mL (22 micrograms). Gonal-f 450 450 IE/0, 75 ml (33 micrograms). 260 $. U.S. about per unit. gonal-f 900 900 IE/1, 5 mL (66 micrograms). Gonal-F 1050 IU/1, 75 mL (77 micrograms). Costs vary.

When treatment with gonal-f begins

Treatment with Gonal-F should be initiated under the supervision of a physician experienced in the treatment of fertility disorders. The following are the more well-known indications

Anovulation, such as women with PCOS (Polycysteus Ovary Syndrome) or women with inadequate ovulatory cycles, whether or not they have used clomiphene citrate (Clomid) or letrozole (Femera) Stimulation with IVF-Cycli, among women who have received vitro fertilization induced an increase in follicles. The purpose of using gonadotropic hypogonadism (HH)gonal is to promote sperm production in men with natural or acquired spermatogenesis problems.

Preventive Measures.

Before taking this product, you should tell your doctor or pharmacist if you are allergic to this or any other product containing FSH or if you have any other allergies.

Gonal-F contains inactive ingredients that may cause allergic reactions or other problems in some people. Consult your pharmacist before use.

Also tell your doctor or pharmacist about your medical situation, especially if you experience or have experienced other fertility or health problems.

Gonal-F may only be administered by well-motivated and well-trained patients. Access to professional advice is important for this. Special attention should be paid to the specific instructions for the first use of the filled pen.

Patients with known hypersensitivity to gonadotrophins that do not contain FSH are at increased risk of cross-sensitivity. Therefore, the first injection of gonal-f should be administered under direct medical supervision.

HOW TO USE

Gonal-F is available in a variety of packages, but preparation and use are literally the same in all cases.

For women undergoing an IVF cycle, the clinic staff will teach them step-by-step how to administer Gonal-F. In any case, it is advisable to read the package leaflets before taking any pictures.

These are the steps that must be followed to administer gonal-f in the correct manner.

1. Reconstitute the product by combining the liquid with the drug until it is homogeneous and free of suspended particles. If particles are present, do not use the product.
2. Place a new needle in the pen and adjust to the prescribed dose.
3. Clean the injection space with alcohol before administering the dose. The lower abdomen is considered the appropriate injection space.
4. Inject gonal-f under the skin or under the muscle as prescribed by the physician.
5. Always discard needles and medical devices.

Gonal-F can be footprinted once daily at the same time each day. To minimize trauma under the skin, it is recommended that the injection space be changed at one time.

This information does not alter the physician’s instructions. Contact your physician if you are concerned that you have administered a very large dose of gonal-f or if you have used it incorrectly.

Dosage

Dosage of gonal-f varies on a case-by-case basis and depending on the treatment being prescribed. The ultimate goal of using this medication is not the same for IVF and IUI cycles, as indicated below.

IUI gonal-f injection

During an IUI cycle, the patient usually undergoes mild stimulation of the ovaries. In fact, the goal is not to stimulate the ovaries, but to produce ovulation, since at least two to three follicles are needed to develop.

Therefore, the dose of gonal-f that is important in an IUI cycle is usually 75 or 150 iu. Daily doses rarely exceed 225 iu.

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Gonal-F injections for IVF/ICSI.

Contrary to what happens in an IUI cycle, IVF patients receive controlled stimulation of the ovaries (cos). In this case, the goal is to obtain 8-15 adult follicles. This can later be collected by the follicular unit. For this purpose, the appropriate dose of gonal-f varies from 150 to 450 once a day.

Regardless of the fertility treatment, the physician plans a series of prognostic visits to evaluate estradiol levels and follicle height. The dose administered can be adjusted according to what the physician sees at each visit.

Whether you need to undergo IUI or IVF to become a mother, we encourage you to request a current fertility report; in three easy steps you will get a list of hospitals that meet your preferences and our strict ownership aspects. Additionally, you will receive an emailed report with tips for your first visit to Fertility Clinic.

Contraindications.

Do not use this product if you are allergic or resistant to follitropin ALFA, FSH, or one of the operating fabrics from which this drug is made.

Additionally, Gonal-F is contraindicated in protective evaluations, where there are good ones.

• Tumors of the hypothalamus or pituitary gland
• Large ovarian cysts not caused by PCOS
• Vaginal blood loss of unknown origin
• Ovarian, uterine or breast cancer
• Lactation or pregnancy
• Major ovarian deficiency or testicular failure originally
• Abnormalities of the female reproductive organs incompatible with pregnancy
• Uterine fibroids that prevent pregnancy.

Furthermore, it must be remembered that gonads are not applicable to children or the elderly.

Interactions & side effects

First of all, it should be understood that no clinically significant interactions between drugs have been reported during treatment with gonal-f.

Nevertheless, Gonadoreline or GnRH are products that may have interactions with gonal-f that increase the dose of gonal-f needed to produce an adequate ovarian response.

Many patients have few side effects effects Others can develop smooth side effects during or after administration of Gonal-F effects or side effects covering reactions to the injection space (bruising, discomfort, pain, swelling, etc.), headache, or occurrence of ovarian cysts.

Side effects of gonal-f

Drug Medical Testing. com. last updated on October 15, 2022.

Note: This document has side effects. effect Information about follicle stimulating hormone. Some doses listed on this page have all occasions not used to create brand Gonal-F.

Used for follicle stimulating hormone: subcutaneous solution powder, subcutaneous solution. Dosages in other forms:

Serious side effects of Gonal-f

Along with the required effects with the follicle-stimulating hormone (the active substance of gonal-f) may be undesirable effects Although not all of these side effects effects action, medical support may be needed.

If you have one of the correct side effects, go to the doctor immediately effects occurs during the use of follicle-stimulating hormone:

More frequent

• Acid or sour stomach
• Restlessness
• lower back pain
• cracking of the abdomen
• Abdominal enlargement
• Pain or stuffiness in the chest
• confusion
• cough
• diarrhea
• Dyspnea
• Trouble
• Dizziness or lightheadedness
• Double vision
• Excess air or gas in stomach or intestines
• Fainting
• Fast heartbeat
• Fast and unstable arms
• Full feeling
• Headache
• Heartburn
• Inability to move arm, leg, or facial muscles
• Stomach complaints
• Decreased appetite
• Noisy breathing
• Passing gas
• Pelvic pain, discomfort, aching, or a feeling of heaviness
• Fast weight gain
• Severe nausea
• Slow speech
• Abdominal pain, discomfort or soreness, or swelling
• Sudden pain in the abdomen or shoulder
• Sweating
• Shortness of breath
• Abnormal or heavy vaginal bleeding
• Uterine bleeding between menstrual periods
• Vomiting or diarrhea

Frequency unknown

• Trouble
• Dizziness
• Hives, itching, skin rash
• Bust pain, gro calves, especially calves
• Swelling or swelling of eyelids, face, lips, or tongue
• Unclear speech
• Sudden loss of coordination
• Sudden strong impotence or numbness in arms or legs
• Unusual fatigue or weakness
• Altered vision

Other side effects of Gonal-f

Some side effects Follicles – Stimulating hormones may occur and usually have no medical support. These symptoms effects for example, can stop during the healing process when the body adapts to the medication. In addition, caregivers can talk about ways to prevent or alleviate some of these problems effects .

Talk to the care provider as one of the relevant parties effects persisting or becoming a nuisance or have questions about it:

More frequent

• acne
• Bleeding, blistering, burning sensation, cold, skin discoloration, pressure sensation, edge, edges, infection, infection, inflammation, itching, bumps, numbness, pain, rash, redness, scarring, stinging, stinging, tingling, tingling, swooning, swearing or heat, shaking, shaking sewing swelling, tenderness, tingling, injection
• rose
• Fat skin
• Swelling of the breasts or painful breasts in both women and girls

Not very common

• Reduced attention to sex
• Inability to obtain or maintain an erection
• Loss of sexual ability, drift, movement or performance

For health care professionals

Applied to follicle stimulating hormone: injectable powder for injection, injectable solution, subcutaneous powder for injection, subcutaneous solution.

Frequent

The most common side effects were headache, ovarian cysts, local injection reactions (e.g., pain, erythema, hematoma, swelling, and/or complaints in the injection space). [Ref].

Genitalia.

Not very rare (>10%): multiple family members (up to 35, 1%), ovarian cysts, non-energetic to moderate ovarian enlargement

Often (1% to 10%): mild to moderate OHS (including symptomatic), intermenstrual bleeding, pelvic complaints, ovarian pregnancy, ectopic pregnancy, miscarriage, gynecological bacteria (male), phycology, vegetative cysts, testicular

Occasional (0, 1% to 1%): loom OHSS (symptomatic), boustecrialim, metrorrhagia, ovarian cysts, ovarian enlargement, ovarian torsion, uterine bleeding, vaginal bleeding

Rare (<0. 1%): slow worsening of OHSS, adnexal torsion associated with ovarian enlargement

Unreported frequency: ectopic pregnancy, miscarriage, multiple pregnancies

Post store report: breast sensitivity [see also].

Gastrointestinal

Very often (>10%): abdominal pain (up to 23, 2%), abdominal enlargement (13, 9%)

Often (1% to 10%): abdominal swelling, abdominal discomfort, nausea, diarrhea, constipation, abdominal pain, decreased, flatulence.

Sometimes (0, 1% to 1%): stuffed abdomen [Ref].

Nervous System.

Very often (more than 10%): headache (up to 26, 5%), dizziness

Local

Very often (more than 10%): injection space reactions (e.g., pain, erythema, hematoma, injection space swelling, / or complaints) [Ref].

Dermatology

Often (1% to 10%): acne, skin rash, skin cysts

Frequently not mentioned: bruising, edema, erythema, ur measles, itching [Ref].

Metabolism

Frequently (1% to 10%): weight gain [Ref].

Hypersensitivity

Occasional (0, 1% to 1%): generalized hypersensitivity reactions

Very Occasional (<0. 01%): non-energetic and severe hypersensitivity reactions, including anaphylactic reactions and shock [REF].

Cardiovascular

Very occasional (<0.01%): thromboembolism, usually associated with serious OHSS [REF].

Other.

Occasional (0. 1% to 1%): pain, flu-like symptoms [REF].

Respiration

Very occasional (<0, 01%): worsening or aggravation of asthma [REF].

Read more about gonal-f (filtered stimulating hormone)

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• Compare alternatives
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Patient Source

• Information about the drug
• gonal-f (advanced lecture)

Other brands

Specialty Sources

Other formulations

Related Treatments

• Hypothyroidism, male
• Follicle Stimulation
• Ovulation Induction

Recommendations

1. “Product Information. Follistim (Folicle – Stimulating Hormone)”. Organ (2002):

2. “Product Information. gonal-f (follicle-stimulating hormone)”. Serono Laboratories Inc (2002):

3. “Summary of UK Product Data”. o 0

4. Cerner Multum, Inc. “Product Information for Australia”. o 0

Other Information

Always consult your care provider to ensure that the information on this page is used for your own incident.

Some side effects Cannot be reported. You can report this information to the FDA.

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