What are estrogen receptor / progesterone receptor (ER/PR) tests ?
Estrogen receptor / progesterone receptor (ER/PR) tests Used to guide the cure of breast cancer. The sensor is a protein that attaches to a specific drug. er/pr tests look for receptors It attaches to hormones estrogen and progesterone in breast cancer tissue samples. Estrogen. and progesterone Plays an important role in female sexual development and reproductive function. Men still have these hormones, but in much smaller amounts.
About 70% of all breast cancers in women receptors that attach to estrogen and/or progesterone About 80% to 90% of all male breast cancers. receptors Breast cancer areas estrogen and/or progesterone receptors Appropriate types include:
- ER Positive (ER+): that one estrogen receptors (ER)
- PR positive (PR+): with cancer progesterone receptors (PR)
- Hormone receptor positive (HR+): cancer that has one or both of these receptors .
Breast cancer that is not there PR receptors called HR-negative (HR-).
ER/PR tests Indicates whether one is PR receptors is in your breast cancer cells. Test results are often referred to as hormonal status. receptor status. As your hormone receptor status indicates that one or both are present receptors cancer cells may respond well to certain types of healing.
Other names: ER/PR IHC tests, hormones. receptor status
What are they used for?
ER/PR tests They are used to manage healing in breast cancer patients.
Why is PR needed? test ?
You may need this test When breast cancer has been determined. Your personal hormone status. receptor status will certainly help you make decisions regarding treatment. If you have a positive, PR positive, or HR positive cancer, substances that lower hormone levels are likely to be very effective because they prevent or hinder the hormones from stimulating the cancer to rise. if you have an HR negative cancer, these types of medications will not work for you. if you have a PR negative cancer, these types of medications will not work for you.
What happens during ER/ PreAl?
Your doctor will need to take a sample of breast tissue in a procedure called a breast biopsy. There are three types of breast biopsies
- Aspiration biopsy with a narrow needle. Free delicate needle to remove a sample of breast cells or fluid
- Core needle biopsy, which uses a huge needle to remove the sample
- Surgical biopsy. Sample is removed in a small outpatient procedure
Biopsy using needle aspiration and core needle usually completes the procedure correctly
- You lie on your side or squat at the exam table.
- The physician cleans the biopsy site and injects anesthetic so there is little or no pain during the procedure.
- After the area has been petrified, the physician will place a delicate suction or biopsy needle at the biopsy site and deliver a tissue or water sample.
- As the sample is taken, a small pressure is felt.
- Pressure will be applied to the biopsy area until the bleeding stops.
- Your doctor will establish a sterile relationship with the biopsy area.
With a surgical biopsy, the surgeon makes a small incision in the skin and removes all or part of the breast tumor. If the tumor cannot be obtained by needle biopsy, a surgical biopsy may be performed. Surgical biopsies are usually accompanied by the necessary scarring.
- You are at the operating table. You will get an injection (intravenous infusion) into your arm or arm bundle.
- You will get a drug that is a calming agent that will surely help you relax.
- You get local or joint anesthesia, which ensures that you feel no pain during the procedure.
- With local anesthesia, the nurse injects the medication into the biopsy area to numb the area.
- With joint anesthesia, the medication is given by an anesthesiologist. You will then be unconscious during the procedure.
What must be done to prepare for anesthesia? the test ?
If local anesthesia (anesthesia in the biopsy area) is obtained, little or no special preparation is required. If you receive joint anesthesia, do not eat or drink for several hours prior to the procedure. Your surgeon will give you more specific instructions. If you have undergone anesthesia or joint anesthesia, you should always ask someone to take you home. You can become confused and distracted after the procedure.
There are risks. the test ?
Minor bruising or bleeding may occur in the biopsy space. The website can make you sick. If this occurs it will be treated with antibiotics. Surgical biopsies can cause additional pain and discomfort. Your doctor may recommend or prescribe medications that will certainly help you feel better.
What do the results mean?
Your results will indicate whether you have a hormone receptor positive or negative cancer picture. If your hormone receptor status is positive, the test levels are also shown of estrogen and/or progesterone receptors . The higher the level, the more of receptors ineffective your hormones are, the more likely certain medications are more effective in curing your cancer. If your hormone receptor status is negative, these medications are not effective.
If you have questions about your results, consult your own physician.
Is there anything else I should know? tests ?
The HER2 test is often done at the same time as the ER/PR test. It is for a specific hormone. receptor Cancer can also be HER2 positive; HER2 is a protein on the surface of all breast cells; treatment of HER2 positive breast cancer is very effective, but not for HER2 negative cancers.
With permission of MedlinePlus from the National Library of Medicine.
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