Cushing s Disease

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In a normal, healthy person, the pituitary gland literally knows when to release the hormone that causes the production of cortisol. This hormone is called adrenocorticotropic hormone (ACTH), and when it is released, cortisol is produced and released into the body. In people with Cushing’s syndrome disease their bodies cannot regulate the amount of cortisol produced, so cortisol is produced in very large amounts.

For example, why?

People of all ages can develop Cushing’s disease, but it occurs most often in people between the ages of 20 and 50, and in women. Yet it is uncommon. disease Only 10-15 out of every million people are diagnosed with the disease each year.

The pituitary gland serves the human brain. As mentioned above, people with Cushing’s syndrome have a disease pituitary gland produces very large amounts of ACTH. This is a chain reaction because during this period the adrenals begin to produce excess cortisol. Cortisol plays an important role in overcoming the common cold and in the way the body uses proteins, fats, and carbohydrates.

In most cases, Cushing’s disease is caused by a tumor of the pituitary gland. disease This is a tumor of the pituitary gland called an adenoma. Generally, these adenomas are benign and relatively small in size. Because these tumors are so small, they are not easily detected and may be diagnosed as Cushing’s syndrome. disease is often delayed.

Are Cushing’s disease and Cushing’s syndrome the same?

You may have heard of the two definitions, Cushing’s disease and Cushing’s syndrome. disease And you thought they were the same. This is actually a mistake, as these are two different diseases that are often lumped together.

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Cushing’s Syndrome: People with Cushing’s Syndrome actually suffer from Cushing’s Syndrome. disease It is believed to be the medical cause of this syndrome. Cushing’s syndrome is a condition in which the body produces excessive amounts of cortisol. This can be caused by the way corticosteroids are administered or by other causes.

Cushing’s disease Cushing’s syndrome is a condition in which a tumor causes the pituitary gland to produce excess ACTH. This excess ACTH affects the adrenal glands, causing them to work excessively and increasing cortisol levels.

However, these are two different disorders and the symptoms may appear the same. Signs of joints are weight gain on the face, belly, and reddish areas forming on the belly.

Symptoms of Cushing’s Disease

Cushing’s disease Cushing’s disease has many symptoms associated with it, and someone may only see one or two of them or can list almost all. It is also important to note that some symptoms are specific to men, while others are specific to women.

Common Symptoms

  • Muscle weakness
  • Fatigue
  • Difficulty with someone’s cognitive skills
  • Irritability, agitation, and/or depression
  • Headaches
  • Problems with emotional regulation
  • Hypertension or changes in blood pressure in a negative way
  • Loss of bone density. In other words, it is easier to get fractions
  • Glucose intolerance, which can eventually lead to diabetes
  • Weight gain in the face, midsection, shoulders and mid-back
  • Cuts and infections heal very slowly
  • Skin is simple and pale
  • Stretch marks that are purple or pink and develop on the arms, chest, thighs and abdomen
  • Acne

Common symptoms in men

  • Erectile dysfunction
  • Decreased fertility
  • Reduced libido

Common Symptoms in Women

  • Irregular or absolutely failing menstruation
  • Increased facial and body hair

Diagnosis of Cushing’s disease

Diagnosis of Cushing’s disease disease It is an important step for someone to receive the next cure which is critical for the disease. What does it actually prepare you for? disease Because the signs are not mild, it actually takes quite a long time for them to occur. Another difficult part of diagnosis is that signs are likely to be noticed in cycles, and depending on the time of testing, this may not be reflected in

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Cushing’s test. disease This is done by an endocrinologist. They will have insight into your blood values and specifically look at your cortisol levels to make sure they do not increase. An MRI may also be important when trying to find a tumor. Keep in mind that many blood tests may need to be done.

Treatment of Cushing’s Disease

Once the disease Once Cushing’s disease has been diagnosed, the physician can prepare an appropriate healing project for each individual. In practice, there are many variations regarding healing.

1. radiation therapy

It is performed on the human pituitary gland and is often considered a good option when the patient already has an operation that has not been successful or cannot arrange the necessary surgery. During this treatment, the patient does not have to remain in the clinic, and it is performed daily in the direction of 4 to 5 months. For example, how it works is that the patient wears a personal mask and is well aligned by radiation therapy.

2. adrenal gland removal

Of course, this surgical option is performed in the clinic. Patients can choose to have the function performed laparoscopically. This is usually an option for those who have not had the opportunity to isolate the tumor on the pituitary gland or who have already tried surgery and were losers.

3. pituitary gland removal

This feature provides a surgical function in which the problem key on the pituitary gland is removed in a complex; it involves a high heat rate of 80% and is performed by a neurosurgical specialist. When the surgeon passes through the nose, there is very little scarring with this procedure.

4. medication

Another option for patients is to take medications that keep cortisol production under control. These pills are specific to the adrenal glands and slow down the production value. This is usually given to patients who are on a waiting list for surgery, for example. This is because they are pre-determined as short-term curative projects. The drugs are ketoconazole and metyrapine.

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Alex Koliada, PhD

Alex Koliada, PhD

Alex Koliada, PhD, is a well-known doctor. He is famous for his studies of ageing, genetics and other medical conditions. He works at the Institute of Food Biotechnology and Genomics NAS of Ukraine. His scientific researches are printed by the most reputable international magazines. Some of his works are: Differences in the gut Firmicutes to Bacteroidetes ratio across age groups in healthy Ukrainian population [BiomedCentral.com]; Mating status affects Drosophila lifespan, metabolism and antioxidant system [Science Direct]; Anise Hyssop Agastache foeniculum Increases Lifespan, Stress Resistance, and Metabolism by Affecting Free Radical Processes in Drosophila [Frontiersin].
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