A BRAF genetic This test uses a sample of tumor tissue, bone marrow, or blood to look for changes in the BRAF gene. A genetic configuration is also referred to as a mutation or mutation of a gene. Analysis is usually performed to look for changes in the BRAF gene that may be involved in cancer.
A gene is a piece of DNA in a cell that you inherit from your protector. Genes have information that keeps you in control of how you look and how your body works; BRAF genes isolate notes and create proteins that tell the cell that it must grow and distribute itself to form new cells.
In certain configurations of the BRAF gene, there is every opportunity to alter the genetic memo and ensure that the actual BRAF protein is very strong. These abnormal BRAF proteins ensure that the cells rise very strongly. As a result, cells with altered BRAF genes have the opportunity to become unruly and cancerous.
Altered BRAF genes and their proteins are usually found in melanoma, the more common skin cancer. This configuration is also seen in other types of cancers, including colorectal, thyroid, ovarian, non-potent, and some blood cancers.
Cancers with altered BRAF genes tend to grow faster than cancers that do not have this genetic configuration. If you know whether your cancer has an altered BRAF gene, your doctor can choose a more effective treatment for you.
BRAF gene alterations can be acquired or inherited.
- Acquired configurations of the BRAF gene occur somewhere after birth; most changes in the BRAF gene are considered acquired. These configurations have the opportunity to occur if the cell makes a mistake when sharing to form a new cell. If you have been exposed to carcinogens, the configurations still have a chance to occur. Acquired genetic configurations occur only in certain cell types. As a rule, they are not present in sperm or eggs and therefore cannot be passed on to children.
- Inherited genetic configurations are the configurations that are displayed. Every cell in the body has a genetic configuration, including the egg and sperm. This means that the configuration can be passed on to one’s own boy.Inherited configurations of the BRAF gene are rare but can increase the risk of cancer or cause any type of of genetic disorders available since birth.
Other names: BRAF gene mutation test, melanoma, BRAF V600 mutation.
What is it used for?
BRAF genetic The test can be used for
- Find the BRAF gene makeup of a particular cancer. This information can be used to draw conclusions about the diagnosis and treatment of a particular cancer.
- Check for the presence of genetic alterations in the BRAF gene. This is not a routine screening test. However, you can use it if your own health or family situation indicates that you are at increased risk for cancer or another condition caused by a genetic change in the BRAF gene. Your risk of developing cancer caused by a genetic change in the gene may be higher if
- You or a family member had cancer at an unusually young age
- You have a parent relative who has the same cancer pattern
- You or a family member has more than one form of cancer.
Why BRAF is needed genetic test
You may need a BRAF genetic test if you:
- There are some cancers that can be caused by changes in the BRAF gene BRAF results genetic This test can help your doctor
- Predict how rapidly your cancer will grow.
- Know if targeted treatments can help you. Targeted therapy for cancers with BRAF gene block or slow, abnormal protein changes that cause cancer growth. These drugs can be harmful when given to cancers that do not have a modified BRAF gene. Thus, a BRAF test is needed to find one of the best cancer drugs for you.
- Understand how your cancer responds to treatments such as chemotherapy and radiation therapy.
If you are considering a BRAF genetic test to look for hereditary genetic changes, a genetic consultant can help you view the pros and cons of this test.
What happens with BRAF genetic test?
If you have BRAF genetic you are tested because you have cancer, the test will depend on the type of cancer you have:
- If you have a large tumor, the test often uses a sample of the tumor cells. The sample can be taken
- During surgery to remove the entire tumor.
- In a biopsy where a small amount of tissue is removed. Which biopsy sample you get depends on where your cancer is located. Biopsies can be done with support.
- A hollow needle inserted into the skin. Ultrasound or other imaging studies can be used to guide the needle.
- A small maneuver to remove tissue reference (incisional biopsy).
If you have BRAF genetic A check to find the hereditary genetic makeup usually yields a blood test.
Do I need to prepare for the test?
If a blood test has been done, usually no special substances are needed. Ask your supplier how to prepare for other types of BRAF gene tests.
Were there any risks involved in the test?
The risks of BRAF gene testing depend on the intent of the selection. Talk to your health care provider about your own risks.
In general, biopsies can cause pain and possible bleeding where tissue has been removed.
Blood tests have fairly little risk. There may be slight soreness or bruising in the area where the needle is inserted, but most signs disappear quickly.
After the bone marrow exam, you may notice that you are stiff, or glued to your bed where the monster was taken. This usually disappears after a few days. Symptoms of non-anterior chamber are very rare, but could be swelling, bleeding in space or fever.
What do the results mean?
If you have a test result with cancer, it will appear as follows
- There is an alteration in the BRAF genome and the doctor has the opportunity to use drugs aimed at altering the BRAF protein that forces the cancer to grow. Other methods may be needed to heal the disease.
- If there is no change in the BRAF genome, the physician will prescribe another method to heal the cancer.
If you do not have cancer and the results show that you have changes in the BRAF genome, this does not mean that you will have cancer. However, depending on your configuration, you may be at an increased risk of developing cancer.
Frequent investigation of your cancer can help lower your risk. For example, to reduce the risk of melanoma, more skin investigations can be done to check the whole body for the presence of other suspicious growths. Screening for cancer can help detect cancer in its early stages when it is easier to treat.
If you have genetic changes in your BRAF genome, talk to your own Internet provider or counselor to recognize your risk for cancer. a genetic advisor who recognizes the risk of passing the change on to your children.
Provided by MedlinePlus at the State Medical Library.
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