What Causes Enlarged Lymph Nodes Under Armpit

Enlarged lymph nodes under the armpit can be a concerning symptom that may indicate an underlying health condition. The lymph nodes are a part of the body’s immune system and can become enlarged in response to infection, inflammation, or even cancer.

One common cause of enlarged lymph nodes in the armpit is infection. Bacterial or viral infections, such as strep throat or the flu, can cause the lymph nodes to swell as the body’s immune system works to fight off the infection. In some cases, a localized infection in the armpit, such as an infected hair follicle or an abscess, can also lead to swollen lymph nodes.

In addition to infection, inflammation can also cause the lymph nodes under the armpit to become enlarged. Inflammatory conditions such as rheumatoid arthritis or lupus may trigger an immune response that results in swollen lymph nodes. Similarly, skin conditions like dermatitis or eczema can cause inflammation in the armpit area, leading to lymph node enlargement.

While less common, an underlying cancer can also cause enlarged lymph nodes under the armpit. Lymphomas, which are cancers of the lymphatic system, can cause the lymph nodes to swell. Breast cancer can also spread to the nearby lymph nodes, causing them to become enlarged. It’s important to note that swollen lymph nodes alone do not necessarily indicate cancer, but it’s essential to get a proper medical evaluation to determine the underlying cause.

In conclusion, enlarged lymph nodes under the armpit can be caused by various factors such as infection, inflammation, or cancer. Identifying the underlying cause is crucial in order to receive appropriate treatment and ensure optimal health. If you notice swollen lymph nodes in your armpit or have any concerns, it’s important to consult with a healthcare professional for further evaluation and diagnosis.

Causes of Enlarged Lymph Nodes Under Armpit

Enlarged lymph nodes under the armpit, also known as axillary lymphadenopathy, can occur due to various reasons. One common cause is infection. When there is an infection or inflammation in the arm, breast, or surrounding areas, the lymph nodes in the armpit can become enlarged as they work to fight off the infection.

Certain types of cancers can also cause enlarged lymph nodes under the armpit. Breast cancer is one such example. As cancer cells spread, they can travel through the lymphatic system and accumulate in the lymph nodes. This can lead to enlargement of the nodes in the armpit.

Another potential cause of enlarged lymph nodes under the armpit is autoimmune disorders. These conditions occur when the immune system mistakenly attacks healthy tissues in the body. This can trigger inflammation and enlargement of the lymph nodes.

In some cases, medication side effects can also lead to enlarged lymph nodes under the armpit. Certain medications, such as those used to treat rheumatoid arthritis or other inflammatory conditions, can cause lymph nodes to swell as a reaction to the medication.

If you notice enlarged lymph nodes under your armpit, it is important to consult a healthcare professional. They can evaluate your symptoms, perform tests if necessary, and determine the underlying cause. Treatment will depend on the specific cause of the enlarged lymph nodes.

Infections

Infections are one of the most common causes of enlarged lymph nodes under the armpit. When a person has an infection, their body’s immune system responds by sending white blood cells to fight off the infectious agents. This can cause the lymph nodes in the affected area, such as the armpit, to become enlarged and tender.

Common infections that can lead to swollen lymph nodes under the armpit include bacterial infections, such as cellulitis or an abscess, and viral infections, such as the flu or mononucleosis. In these cases, the enlarged lymph nodes are a sign that the body is actively fighting off the infection.

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In some cases, the infection may be localized to the armpit area, such as in cases of folliculitis or infected sweat glands. These types of infections can cause the lymph nodes in the armpit to become enlarged as they work to clear the infection.

If you have enlarged lymph nodes under your armpit that are accompanied by other symptoms of infection, such as fever or pain, it is important to see a healthcare provider for further evaluation and treatment.

Lymphoma:

Lymphoma is a type of cancer that affects the lymphatic system, which is a part of the immune system. It occurs when certain white blood cells called lymphocytes grow and divide abnormally, forming tumors in the lymph nodes and other lymphatic tissues. Lymphoma can be classified into two main types: Hodgkin lymphoma and non-Hodgkin lymphoma.

Hodgkin lymphoma is characterized by the presence of Reed-Sternberg cells, which are large abnormal cells found in the lymph nodes. It usually starts in a single lymph node and then spreads to nearby lymph nodes and other organs. Symptoms of Hodgkin lymphoma include enlarged lymph nodes, fever, weight loss, night sweats, fatigue, and itching.

Non-Hodgkin lymphoma is a more common type of lymphoma and can occur in any lymph node or lymphatic tissue. It can be aggressive or indolent, and there are many different subtypes. Symptoms of non-Hodgkin lymphoma include swollen lymph nodes, fever, night sweats, fatigue, unexplained weight loss, and itching.

The exact cause of lymphoma is unknown, but there are several risk factors that may increase the likelihood of developing the disease. These include a weakened immune system, exposure to certain chemicals and toxins, certain infections like Epstein-Barr virus and HIV, and a family history of lymphoma. Treatment for lymphoma may include chemotherapy, radiation therapy, targeted therapy, immunotherapy, or stem cell transplantation, depending on the type and stage of the disease.

Breast Cancer

Breast cancer is a type of cancer that starts in the breast cells. It is the most common cancer among women worldwide, but it can also affect men. This cancer usually begins in the milk ducts or lobules of the breast.

The causes of breast cancer are not fully understood, but there are certain risk factors that can increase the chances of developing the disease. These risk factors include family history of breast cancer, certain genetic mutations, hormonal factors, obesity, and age, among others.

Symptoms of breast cancer may include a lump or thickening in the breast or under the armpit, changes in the size or shape of the breast, nipple discharge, changes in the skin of the breast or nipple, and persistent breast pain or discomfort.

Diagnosis of breast cancer usually involves a combination of mammography, ultrasound, and biopsy. Mammography is the most effective screening tool for detecting breast cancer at an early stage.

Treatment for breast cancer depends on the stage and type of cancer, as well as other factors such as the patient’s overall health and preferences. Treatment options may include surgery, radiation therapy, chemotherapy, hormone therapy, or targeted therapy.

Prevention plays a crucial role in reducing the risk of developing breast cancer. This includes regular breast self-exams, clinical breast exams, mammograms, maintaining a healthy weight, exercising regularly, limiting alcohol consumption, and avoiding smoking.

Inflammatory Conditions

Enlarged lymph nodes under the armpit can be caused by various inflammatory conditions. These conditions occur when the body’s immune system responds to an infection or injury in the armpit area. Inflammation in the lymph nodes is a common reaction to the presence of bacteria, viruses, or other pathogens.

Some common inflammatory conditions that can cause enlarged lymph nodes under the armpit include:

  • Infection: Bacterial or viral infections can lead to swelling and inflammation of the lymph nodes in the armpit. Common infections include strep throat, mononucleosis, and cellulitis.
  • Infected sweat glands: Inflammation of the sweat glands in the armpit can result in enlarged lymph nodes. This can occur due to bacterial infection or blockage of the sweat ducts.
  • Dermatitis: Inflammation of the skin in the armpit, known as dermatitis, can cause the nearby lymph nodes to enlarge. Irritants like harsh soaps, deodorants, or allergic reactions can trigger this condition.
  • Inflammatory breast cancer: In rare cases, enlarged lymph nodes under the armpit may be a sign of inflammatory breast cancer. This aggressive form of breast cancer can cause swelling, redness, and warmth in the affected breast, along with enlarged lymph nodes.
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It is important to consult a healthcare professional if you notice any significant or persistent enlargement of lymph nodes in the armpit.

Autoimmune Disorders

Autoimmune disorders are a group of diseases characterized by an abnormal immune response of the body against its own organs or tissues. These disorders occur when the immune system mistakenly attacks healthy cells and tissues, leading to inflammation and damage. One common manifestation of autoimmune disorders is the enlargement of lymph nodes under the armpit.

There are various autoimmune disorders that can cause enlarged lymph nodes under the armpit. One example is rheumatoid arthritis, a chronic inflammatory disease that primarily affects the joints. In rheumatoid arthritis, the immune system targets the synovial lining of the joints, leading to swelling and destruction of the tissues. This immune response can also result in the enlargement of lymph nodes in the nearby areas.

Another autoimmune disorder that can cause enlarged lymph nodes under the armpit is systemic lupus erythematosus (SLE). SLE is a chronic autoimmune disease that can affect multiple organs, including the skin, joints, kidneys, and heart. In SLE, the immune system produces antibodies that target the body’s own cells and tissues, leading to inflammation and damage. The inflammation can affect the lymph nodes, causing them to enlarge.

In addition to rheumatoid arthritis and SLE, other autoimmune disorders such as Sjögren’s syndrome, Hashimoto’s thyroiditis, and psoriasis can also cause enlarged lymph nodes under the armpit. These disorders involve the immune system targeting specific organs or tissues, leading to inflammation and swelling.

It is important for individuals experiencing enlarged lymph nodes under the armpit to seek medical attention for proper diagnosis and treatment. A healthcare professional can assess the symptoms, perform necessary tests, and provide appropriate management strategies based on the underlying autoimmune disorder.

Allergic Reactions

Allergic reactions can occur when the immune system overreacts to a harmless substance, such as pollen, animal dander, or certain foods. When a person with allergies comes into contact with these triggers, their immune system releases chemicals that cause inflammation and other symptoms. These reactions can affect different parts of the body, including the skin, respiratory system, and digestive system.

Common symptoms of allergic reactions include itching, rash, hives, swelling, sneezing, stuffy or runny nose, watery eyes, coughing, wheezing, difficulty breathing, and gastrointestinal issues. These symptoms can range from mild to severe, and the severity can vary from person to person.

There are several types of allergies, including seasonal allergies (hay fever), allergic rhinitis, food allergies, drug allergies, and insect sting allergies. Seasonal allergies are often caused by exposure to pollen or mold spores, while allergic rhinitis refers to allergies triggered by substances in the air, such as dust mites, pet dander, or smoke.

Managing allergies usually involves avoiding triggers as much as possible and taking medications to relieve symptoms. Antihistamines can help reduce itching, sneezing, and runny nose, while nasal corticosteroids can help with congestion. In severe cases, an allergic reaction may require emergency medical attention, and a person may need to carry an epinephrine auto-injector (such as an EpiPen) to treat severe allergic reactions.

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Alex Koliada, PhD

Alex Koliada, PhD

Alex Koliada, PhD, is a well-known doctor. He is famous for his studies of ageing, genetics and other medical conditions. He works at the Institute of Food Biotechnology and Genomics NAS of Ukraine. His scientific researches are printed by the most reputable international magazines. Some of his works are: Differences in the gut Firmicutes to Bacteroidetes ratio across age groups in healthy Ukrainian population [BiomedCentral.com]; Mating status affects Drosophila lifespan, metabolism and antioxidant system [Science Direct]; Anise Hyssop Agastache foeniculum Increases Lifespan, Stress Resistance, and Metabolism by Affecting Free Radical Processes in Drosophila [Frontiersin].
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