Klor-Con M20

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Medical Testing with Drugs. com. last updated on December 1, 2022.

Klor-Con M20 (Oral).

Potassium is a mineral that is needed for various functions of the body before it beats the heart.

Potassium chloride is used to prevent or treat low potassium levels in the blood (hypokalemia). Potassium levels can become low as a result of illness or the use of certain drugs, or after prolonged illness of diarrhea or vomiting.

Potassium chloride can also be used for purposes not listed in this drug guide.

Usage.

What is Klor-Con M20 (oral) used for?

• Hypokalemia
• Prevention of hypokalemia

Warning.

What very important information do you owe about Klor-Con M20 (Oral)?

There is no obligation to use potassium chloride if you are allergic to it or if

• The potassium content in your blood is increased (hyperkalemia). or
• Diuretics such as amiloride, spironolactone, or triamterone (water rounds) are used.

Tell your doctor if you have ever suffered from

• Heart problems;.
• High blood pressure;.
• Liver or kidney problems;.
• Severe tissue damage; it looks like a serious burn.
• Electrolytes are out of balance (for example, too little calcium or magnesium in the blood).
• Swallowing problems;.
• Slow digestion;.
• Abdominal or intestinal gastric bleeding, ulceration, or obstruction;
• Adrenal gland disorders; or
• Diabetes; or
• Severe dehydration.

Tell your own doctor if you are pregnant or breastfeeding.

User’s Latrothon and Rating

General Evaluation of Klor-conm20 (Oral)

Side effects
Easy to use
Effectiveness

Side effects

What are the side effects of Klor-Con M20 (Oral)?

Call for medical assistance immediately if you show symptoms of an allergic reaction: hive; rough breathing; swelling of the face, lips, tongue, or throat.

Stop using potassium chloride and call your own doctor immediately if you are suffering from

• Serious throat complaints;.
• Chest pain; difficulty breathing.
• Pain, burning heat, bruising, swelling, discomfort, or skin composition during injection.
• Bloated abdominal sensation, powerful nausea, powerful abdominal pain.
• High potassium levels – sensitivity, impotence, affection, chest pain, irregular heartbeat, loss of motion. OR
• Signs of gastric bleeding – Puffy or tourniquet stools, vomiting blood, or broken looks like a coffee pigeon.

Common side effects include

• Nausea, nausea, diarrhea; or
• Gas, abdominal pain; or
• The appearance of potassium chloride tablets in the stool.

This is not an absolute list of side effects; there are good chances for other side effects. Ask your own doctor about side effects; you can report side effects to the FDA at 1-800-FDA-1088.

Pregnancy and Breastfeeding

Can I take Klor-Con M20 (Oral) if I am pregnant or breastfeeding?

Tell your own doctor if you are pregnant or breastfeeding.

Interchange.

Which medications and foods should I ignore while using Klor-Con M20 (oral)?

Do not use potassium supplements or other foods containing potassium unless your doctor tells you to. Salt substitutes or low-salt foods often contain potassium. Read the label of each food or medication to see if it contains potassium.

Recommendations and Dosing Guidelines

How should I take Klor-Con M20 (oral)?

Use Klor-Con M20 (oral) literally as indicated on the label or as prescribed by your physician. Do not use larger or smaller amounts or more than recommended.

Follow all instructions regarding your own prescription label and read all medication instructions or package leaflets. Your doctor may change your dose from time to time. Use the medication literally as prescribed.

Oral potassium chloride is taken by mouth. Potassium chloride injection is given as a slow IV infusion in a vein.

Your care provider will give you this injectable drug if you have a very low potassium content. Tell your care provider if you are experiencing a burning sensation, pain, or swelling around the injection needle when potassium chloride is being administered.

If the drug prints the stomach, take potassium chloride orally with food.

Always follow the directions on the drug label for how to give this medication to your child.

Take the pill or capsule with a glass of water.

Do not make pills or potassium capitals fine. Do not chew it, do not smoke it. Sucking the pill may confuse the eater or slicker.

Identify liquid medicine carefully. Use the supplied dosing atomizer or use the dosing size of the medicine (no kitchen spoon). Take it before you take it.

Special diets may need to be followed when using potassium chloride. Follow all your doctor’s or nutritionist’s instructions. Learn about foods you can eat or ignore to keep your condition under control.

Call your doctor if you have difficulty taking chloride capsules or tablets. You can dissolve the pills in water or mix the capsule drink with a smooth meal. Pay attention to your doctor’s instructions.

Periodic physical examinations may be required. Heart function can be checked with an EKG or ECG (also called an EKG). Even in the absence of symptoms, tests can help the physician determine if medications are effective.

Some pills have a cover that is not absorbed or dissolved by the body. Some of these shells may end up in your stool. This is not a bad thing and does not reduce the effectiveness of the drug.

Store at room temperature, away from moisture, warmth, and light. Keep drink in closed package.

What should I do if I want to spread the dose of Cloric-conM20 (orally)?

Take the medication as soon as possible, but skip the missed dose in case it is time for the correct dose. Do not take two doses at the same time.

klor-con m prescribing information

Medical Testing with Drugs. com. last updated on December 1, 2022.

On this page.

• Description
• Clinical Pharmacology
• Indications and Uses
• Contraindications
• Warnings
• Precautions
• Information on Patient Guidance
• Medication Interactions
• Adverse Reactions
• Overdose
• Medication and Administration
• Delivery/ Storage and Treatment Methods

klor-con m Description

Klor-Con®M10 (Potassium Extended-Release Tablets, USP) – This is an essential oral dose of potassium chloride extended-release tablets specifically featuring 750 mg of microjuice potassium chloride, USP, equal to 10 mg potassium meshes in the tablet.

Klor-con®M15 (Potassium Chloride Tablets with Extended Release, USP) – This is exactly the essential oral dose of potassium chloride with extended release containing 1125 mg of microhapsed potassium chloride, which corresponds to 15 meq potassium. Tablet.

Klor-Con®M20 (Potassium Chloride Tablets with Extended Release, USP) – This is an impossible oral dose of potassium chloride with extended release, specifically containing 1500 mg of microring encapsulated potassium chloride, USP.

These preparations are designed to inhibit the release of potassium, thus minimizing the potential for high potassium chloride concentrations in the gastrointestinal tract, for example.

Klor-Con®M is considered an electrolyte. The chemical name of the concentrated component is potassium chloride and its structural formula is KCl. Potassium chloride, USP, is found as a whitish, particulate powder or dull crystals. It is tasteless and has a salty taste. Findings are neutral from litmoes. It is readily soluble in water and insoluble in alcohol.

Klor-con®M is a pill (not an enteric coating or cleaning matrix) that personally contains trace-gauge potassium chloride crystals that disintegrate when the pill is broken apart. in simulated stomach water at 37°C and in the absence of external agitation, Klor-con®M will, after a few seconds begin to disintegrate into microringer pull crystals, which disintegrate after 1 minute. The microfluidic crystals are designed for improved release of the USP of potassium chloride.

Inactive ingredients: crosmellose sodium, ethylcellulose, and microcrystalline cellulose.

Klo r-Con M-Clinical Pharmacology

Potassium is considered the most important intracellular cation in most body tissues. Potassium ions are involved in many important physical processes, including the conservation of intracellular concentrations. Delivery of nerve impulses; reduction of cardiac, skeletal, and smooth muscle. Preservation of normal renal function.

Intracellular potassium concentrations are approximately 150-160 meq per liter. Normal plasma concentration of adult potassium is 3-5 mg-EQ per liter. Functional ion transport systems maintain this gradient across the plasma membrane.

Potassium is considered a common nutrient, and the steady-state criterion is the amount of potassium taken via the gastrointestinal tract exactly equal to the amount excreted via the urinary tract. Normal potassium intake via the menu is 50-100 meq per day.

Potassium depletion occurs when potassium excretion by the kidneys and/or gastrointestinal excretion is greater than potassium intake. This depletion is usually the result of diuretic therapy, primary or secondary hyperaldosteronism, diabetic ketosidosis, or inadequate potassium replacement in patients receiving prolonged parenteral food. Depletion may develop quickly with difficult diarrhea, especially if accompanied by vomiting. Potassium depletion as a result of these bases is usually accompanied by simultaneous loss of chloride and has hypokalemia and metabolic alkalosis. Potassium depletion can lead to impotence, fatigue, irregular or good cardiac rhythm (especially ectopic rhythm), pronounced u-waves on the ECG, improved cases – cold paralysis and/or lack of urinary accumulation.

If the potassium depletion associated with metabolic alkalosis cannot be treated by correcting the underlying cause of the deficiency, for example, if the patient continues on long-term diuretic therapy, potassium supplementation in the form of a diet with high potassium or potassium levels may restore Normal potassium levels.

In rare life conditions (patients with renal tubular acidosis), potassium depletion may be accompanied by metabolic acidosis and hyperchloremia. In these patients, potassium replacement must be done with non-chloride potassium salts such as potassium bicarbonate, potassium citrate, potassium acetate, or potassium gluconate.

Indications and Dosing of Klor-con m

Due to reports of gastrointestinal and gastric ulcers and substances associated with bleeding in the manufacture of potassium chloride, these substances should be reserved for patients who cannot tolerate or refuse or have problems with watery or lively potassium substances. These substances.

1. for the treatment of hypokalemic patients with or without metabolic alkalosis in cases of inflammatory inflammation and in paralyzed patients with hypokalemia. If hypokalemia is considered a consequence of diuretic therapy, the use of low-dose diuretics should be considered; 2. to prevent hypokalemia in patients at special risk when hypokalemia occurs, such as digital patients and patients with significant cardiac arrhythmias.

Potassium salt administration in patients receiving diuretics for complicated essential hypertension is often unnecessary if these patients have a normal diet and are used as low-dose diuretics. However, serum potassium can be checked from time to time, and if hypokalemia occurs, potassium support supplements are at every opportunity to combat the more adaptive variants. In more severe cases, and when adjusting diuretic doses is not effective or justified, the addition of potassium salts may prove

Contraindications

Potassium supplementation is contraindicated in patients with hyperkalemia because subsequent increases in serum calendar concentrations in these patients can cause cardiac arrest. Hyperkalemia is associated with acquired renal failure, systemic acidosis such as diabetic acidosis, acute dehydration, severe burns, miracles, or extensive tissue collapse such as the administration of potassium diaphragm (e.g., over.

Formulations with regulated release of potassium chloride have caused gastrointestinal ulcers in some cardiac patients with compression of the gastrointestinal tract due to elevation of the left chest. Potassium supplementation, when prescribed for these patients, should be administered as a watery product or as an aqua (watery) suspension of potassium chloride [see NOTE: Patient Information and Dosage and Administration].

All fixed oral doses of potassium chloride are contraindicated in patients with structural, pathological (e.g., diabetic gastric insufficiency paralysis) or pharmacological (affecting the anticholinergic effect in anticholinergic effects required for use of anticholinergic agents or other anticholinergic properties). Passage of tablets through the gastrointestinal tract.

Warnings

Hyperuria.

In patients with impaired potassium excretory organs, absorption of potassium salts may cause hyperkalemia and cardiac arrest. This is most common in patients receiving potassium intravenously, but can also occur in patients receiving oral potassium. Hyperkalemia develops quickly and can be asymptomatic. Administration of potassium salts in patients with acquired renal or other diseases that urgently exacerbate potassium excretion requires more careful prediction of serum potassium concentrations and corresponding adjustment of doses.

Potassium-diuretic interactions.

Hypokalemia should not be considered when potassium salts are administered concurrently with potassium diabetics (such as spironolactone, triamteide, or amiloride), as concurrent administration of these agents can cause severe hyperkalemia.

Interactions with inhibitors of the renin – angiotensin – aldosterone system

Medications that inhibit the renin – angiotensin – aldosterone system (RAAS), including angiotensinemers (ACEs), angiotensin receptor blockers (ARBs), spironolactone, eppendrenone or aliskiren, produce potassium maintenance through aldosterone production. At the same time, carefully monitor potassium in RAAS-treated patients.

Interactions with Nonsteroidal Anti-inflammatory Drugs

Nonsteroidal anti-inflammatory drugs (NSAIDs) may cause potassium maintenance by reducing renal synthesis of prostaglandin E and failure of the renin-angiotensin system; carefully check potassium in patients treated concurrently with NSAIDs; check potassium in patients treated concurrently with NSAIDs; check potassium in patients treated concurrently with NSAIDs; check potassium in patients treated concurrently with RAAS

Gastrointestinal lesions

Potassium chloride in fixed oral form may cause gastrointestinal ulcers and/or stenotic lesions. Based on spontaneous reports of adverse effects, potassium chloride with enteric coating has been associated with an increased incidence of small intestinal lesions (40-50 per 100, 000 patient-years) compared to matrix formulations with prolonged release (40-50 per 100, 000 patient-years patient-years), compare, compare These products, washing matrix or gastrointestinal treatment products are not immediately available; Klor-con M is a tablet designed to provide controlled release of microchap potassium chloride, and therefore, minimize the risk of high local potassium concentrations close to the gastrointestinal wall.

Prospective testing was performed by normal human volunteers whose upper gastrointestinal tract was examined endoscopically before and after a week of therapy with oral chloride. The ability of this model to predict actions that will appear in medical routine practice is unknown. Tests approaching medical routine practice did not reveal precise differences between the cleaning matrix and microhair style formulations. On the other hand, we observed a higher incidence of lesions in the stomach and in the thin intestine. This was observed when receiving the highest doses of the controlled declaration formulation of the washing matrix on criteria not consistent with routine or correct clinical practice (i.e., per 96 mg per 96 mg per 96 mg per distribution distribution distribution distribution distribution distribution distribution distribution distribution distribution in the distribution in the distribution in the distribution in the distribution in the distribution in the distribution in the distribution in the distribution in the distribution in the distribution in the distribution in the distribution in the distribution in the distribution in the distribution in the distribution in the distribution in the distribution in the distribution in the distribution in the distribution in the distribution in the distribution in the distribution in the distribution in the distribution in the distribution in the distribution in the distribution in the distribution in the distribution in the distribution in the distribution in the distribution in the distribution in the distribution in the distribution in the distribution in the distribution in the distribution in the distribution in the distribution in distributed on distributed on distributed on distributed on distributed on distributed on distributed on distributed on distributed on distributed on distributed on distributed on distributed on distributed on distributed on distributed on distributed on distributed on distributed on distributed on distributed on distributed on distributed on distributed on distributed on distributed on distributed on distributed on distributed on distributed on distributed on distributed on distributed on distributed on distributed on distributed on distributed on distributed Divided by Divided by Divided by Divided by Divided by Divided by Divided by Divided by Divided by Divided by Divided by Divided by Divided by Divided by Divided by Divided by Divided by Divided by Divided by Divided by Divided by Divided by Divided by (To slow gastric emptying). Upper gastrointestinal loss observed in favor of endoscopy was asymptomatic and not accompanied by evidence of bleeding (semi-decompensation). The relevance of these results for the normal criteria used (i.e., nontaxable, anticholinergic, lowest dose, lowest dose) along with regulated release of potassium chloride products is considered uncertain. Epidemiologic tests show no increased risk compared to products with microencapsulation to lose in the epigastrium.

Metabolic acidosis

Hypokalemia in patients with metabolic acidosis can be treated by supporting basic potassium salts such as potassium bicarbonate, potassium citrate, potassium acetate, or potassium gluconate.

Precautions

In general.

The diagnosis of potassium depletion is usually made by the presentation of hypokalemia in a patient with medical conditions suggesting an underlying potassium depletion. When interpreting serum potassium levels, the physician should keep in mind that acute alkalosis itself can cause hypokalemia if systemic potassium is not deficient, but acute acidosis itself can increase serum potassium concentrations in the normal spectrum. Total body potassium is decreased. Treatment of potassium depletion, especially in the presence of heart disease, kidney damage, or acidosis, requires attention to the patient’s acid-base balance and corresponding prognosis of serum electrolytes, ECG, and clinical status.

Patient Information

The physician is obliged to consider the possibility of reminding the patient of his rights.

Take every dose with food and absolute glass of water or other water.

Take every dose without crushing, chewing or sucking the pills. If these patients have difficulty swallowing the entire pill, they can try one of the other appropriate dosing methods.

Cut the round pills in half and break both halves apart with water. Pregnant to water (water) suspension as follows: 1. Place the pills (ren) in about ½ cup water (4 liquids); 2. Break apart the pills for about 2 minutes; 3. Stir about ½ after the pills (ren) are broken apart; 4. Soak the suspension and immediately drink the full contents of the glass

Any watery suspension of potassium chloride that is not immediately absorbed should be discarded. The use of other liquids to suspend potassium chloride pills is not recommended.

This medication should be taken according to the frequency and number of doses prescribed by the physician. This is even more important if the patient is still taking diuretics or dermatitis preparations.

If there is any other confirmation of stump or gastrointestinal bleeding on the stump, contact the physician immediately.

Clinical Examination

If blood is drawn for plasmacalcium analysis, it is essential to accept that an increase in relics may occur as a result of an incorrect method of venous injury or hemolysis of the vitro standard.

Medication Interactions

Potassium diuretics, angiotensin enzyme inhibitors [see Warnings].

Carcinogenesis, mutagenesis, and non-obesity

There are no studies on carcinogenicity, mutagenicity, or fertility in animals.

Potassium is considered a common food constituent.

Pregnancy

There are no reproduction studies in animals containing potassium chloride. It is almost impossible for potassium supplements that do not result in hyperkalemia to adversely affect the fetus or affect reproductive performance.

Latent mothers.

The normal potassium ion in breast milk is 13 meq per liter. Since oral potassium is part of the body potassium pool, potassium chloride supplementation should be negligible or have no effect on the potassium content of breast milk.

Pediatrics

Safety and efficacy in pediatric patients have not been determined.

Geriatric

Clinical studies on potassium chloride have not included the required number of subjects over the age of 65 to determine if they respond differently than younger subjects. Another clinical skill reported showed no difference in response between older and younger patients. In general, the greater frequency of decreased liver, kidney or heart function, concurrent disease or other pharmacologic therapies requires careful selection for older patients, usually starting at the bottom of the dosing spectrum.

This product is known to be quite differentiated by the kidneys, and the risk of toxic reactions to this product may be greater in patients with reduced renal function. Elderly patients are at greater risk for reduced renal function, so concern about dose selection is a footnote.

Side Effects.

Hyperkalemia is considered one of the most common side effects [see Contraindications, Warnings, and Overdose]. There have also been reports of upper and lower gastrointestinal criteria, including obstruction, bleeding, ulceration, and perforation [see Contraindications and Warnings]. The most common side effects of oral potassium salts are nausea, flatulence, abdominal pain/ discomfort, and diarrhea. These symptoms are associated with irritation of the gastrointestinal tract and are more dilutional in preparation than any other symptom, with doses taken by way of eating or reducing the number taken at a time.

Overdose

Administration of oral potassium salts to people with normal potassium partitioning mechanisms can cause severe hyperkalemia. However, fatal hyperkalemia can occur if the elimination mechanism is disturbed or if potassium is administered intravenously very rapidly [see Contraindications and Warnings]. It is important to recognize that hyperkalemia is usually asymptomatic and is manifested only by increased serum calendar concentrations (6.5-8.0 mg-EQ/L) and associated ECG changes (peak T wave, loss of P wave, P wave loss, depression, depression of depression). S-T-S segment and QT interval dilation). Late manifestations are muscle paralysis and mental and vascular collapse due to cardiac arrest (9-12 meq/l).

A curative measure of hyperkalemia is appropriate:

Patients should be meticulously checked for the presence of arrhythmias and electrolyte changes.

1. elimination of potassium-containing products and medications and all those with potassium properties, such as potassium diuretics, ARBs, ACE inhibitors, NSAIDs, and certain dietary supplements; 2. if the patient is not at risk for developing inflammatory toxicity or low calcium gluconate; 3. 1000 mL Intravenous administration of 300-500 mL/hour of 10% dextrose solution containing 10-20 units of crystalline insulin per 1000 mL; 4. correction of acidosis, if present, intravenous sodium bicarbonate; 5. introduction of resin, hemodialysis, or peritoneal dialysis; 6. treatment of hyperkalemia with a single dose of sodium gluconate, if the patient is not at risk of developing inflammatory toxicities; and 7. treatment with a single dose of sodium bicarbonate.

In the treatment of hyperkalemia, it should be remembered that in patients stable with dermatitis, a very rapid drop in serum calender concentration may lead to dermatitis toxicity.

The extended release characteristic means that there is an opportunity for absorption and toxic effects to reverse in the direction of several hours. Let us look at the usual measurements for removing an immediate product.

Dosage and administration of klor-con m

The normal dietary potassium intake for the average adult is 50 to 100 mg EQ per day. Depletion of potassium sufficient to cause hypokalemia usually requires more than 200 MEQ potassium from the body store.

The dosage should be adapted to the individual needs of each patient; the dose of Phypokalai a-Prophylaxis is usually 20 meq per day. To cure potassium depletion, doses of 40 to 100 meq or more per day are used; if more than 20 meq per day is given, the dose should be divided if only 20 meq is given at one time per term.

Each Klor-Con® M10 tablet contains 750 mg of potassium chloride, equivalent to 10 mg of potassium.

Klor-Con® M15 tablets contain 1125 mg of potassium chloride, which is equivalent to 15 mg of potassium.

Each Klor-Con® M20 tablet contains 1500 mg of potassium chloride, which is equivalent to 20 mg of potassium.

Klor-Con M tablets should be taken with food or with a glass of water or other water. Do not take this product on an empty stomach due to the risk of stomach irritation (see Warnings).

Patients who have difficulty swallowing tablets whole may try one of the other appropriate dosing methods.

Cut the round pills in half and break both halves apart with water. Pregnant to water (water) suspension as follows: 1. Place the pills (ren) in about ½ cup water (4 liquids); 2. Break apart the pills for about 2 minutes; 3. Stir about ½ after the pills (ren) are broken apart; 4. Soak the suspension and immediately drink the full contents of the glass

Do not take Potassium Chloride Aqueous Suspension immediately and discard. Use of other potassium chloride suspensions is not recommended.

How is Klor-Con M delivered?

Klor-Con® M20 extended-release tablets contain 1500 mg of potassium chloride (equivalent to 20 mg potassium). They are white rectangular tablets marked “KC M20”. They are delivered in the following ways

Pack of 10 tablets, NDC 55154-5634-0.

Store at 20-25°C (68-77°F); temperature differences of 15°-30°C (59°-86°F) are acceptable [U. S. Pharmacopeia controlled room temperature].

Store in a tightly closed container.

Manufactured by UPSHER-SMITH LABORATORIES, LLC, Maple Grove, MN 55369.

Klor-Con and Micro-Dispersible Technology are considered registered trademarks of Upsher-Smith Laboratories, LLC.

This product may be the subject of one or more U.S. patents, see www. Our Patents. Com.

Certain production operations are performed by other companies.

Dublin, Ohio 43017.

Reflective panels for packaging and labeling

Potassium Chloride Extended Release Tablets, USP

Cardinal Health 107, LLC

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• Hypokalemia
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